9SAK
Crystal structure of SARS-CoV-2 NSP14 in complex with compound 6
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine-N7 methyltransferase nsp14 | polymer | 525 | 59560.2 | 1 | UniProt (P0DTD1) Pfam (PF06471) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 14,nsp14,Proofreading exoribonuclease nsp14,ExoN |
| 2 | B (B) | Guanine-N7 methyltransferase nsp14 | polymer | 525 | 59576.2 | 1 | UniProt (P0DTD1) Pfam (PF06471) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 14,nsp14,Proofreading exoribonuclease nsp14,ExoN |
| 3 | C, R (A, B) | (2~{R},3~{R},4~{S},5~{S})-2-(6-aminopurin-9-yl)-5-(naphthalen-2-ylsulfanylmethyl)oxolane-3,4-diol | non-polymer | 409.5 | 2 | Chemie (A1JMZ) | |||
| 4 | D, E, F, S (A, B) | IMIDAZOLE | non-polymer | 69.1 | 4 | Chemie (IMD) | |||
| 5 | G, H, T, U, V... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 6 | I, J, K, L, M... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 7 | AA, N, O, P, Q... (B, A) | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) | |||
| 8 | BA, CA (A, B) | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
A: 1 - 525 (UniProt: P0DTD1)
B: 1 - 525 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ala 90 | Asp 6015 | conflict |
| Ala 92 | Glu 6017 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 90 | Asp 6015 | conflict |
| Ala 92 | Glu 6017 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 119136.3 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 2138.3 | |
| All* | Total formula weight | 121274.6 |
