9SAJ
Crystal structure of SARS-CoV-2 NSP14 in complex with compound 5
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Guanine-N7 methyltransferase nsp14 | polymer | 525 | 59544.2 | 2 | UniProt (P0DTD1) Pfam (PF06471) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 14,nsp14,Proofreading exoribonuclease nsp14,ExoN |
| 2 | C, D, E, G, O... (A, B) | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) | |||
| 3 | F, H, K, S (A, B) | IMIDAZOLE | non-polymer | 69.1 | 4 | Chemie (IMD) | |||
| 4 | I, J, L, R, T... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 5 | M, Y (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | N, Z (A, B) | 1-[2-[[(2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]ethyl]-3-ethyl-urea | non-polymer | 397.5 | 2 | Chemie (A1JMY) | |||
| 7 | AA, BA (A, B) | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 525 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ala 90 | Asp 6015 | conflict |
| Ala 92 | Glu 6017 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 119088.3 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 2158.6 | |
| All* | Total formula weight | 121246.9 |
