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9S83

Crystal structure of de novo designed binder JUBO4 and the LEDGF PWWP domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
JUBO4polymer748006.81synthetic construct
2B
(B)
PC4 and SFRS1-interacting proteinpolymer9110426.91UniProt (O75475)
Pfam (PF00855)
Homo sapiens (human)CLL-associated antigen KW-7,Dense fine speckles 70 kDa protein,DFS 70,Lens epithelium-derived growth factor,Transcriptional coactivator p75/p52
3C
(B)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
4D, E
(A, B)
waterwater18.0128Chemie (HOH)
Sequence modifications
B: 1 - 90 (UniProt: O75475)
PDBExternal DatabaseDetails
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight18433.7
Non-Polymers*Number of molecules1
Total formula weight62.1
All*Total formula weight18495.8
*Water molecules are not included.

258009

PDB entries from 2026-08-12

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