9S70
Crystal structure of RXR alpha LBD bound to a partial agonist 21 and a coactivator fragment SRC1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Retinoic acid receptor RXR-alpha | polymer | 235 | 26353.6 | 1 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (human) | Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha |
| 2 | B (B) | Nuclear receptor coactivator 1 | polymer | 21 | 2431.8 | 1 | UniProt (Q15788) | Homo sapiens | NCoA-1,Class E basic helix-loop-helix protein 74,bHLHe74,Protein Hin-2,RIP160,Renal carcinoma antigen NY-REN-52,Steroid receptor coactivator 1,SRC-1 |
| 3 | C (A) | 3-[[4-cyclobutyl-6-(3,4-dihydro-2~{H}-quinolin-1-yl)pyrimidin-2-yl]amino]propanoic acid | non-polymer | 352.4 | 1 | Chemie (A1JL7) | |||
| 4 | D (A) | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence modifications
A: 229 - 462 (UniProt: P19793)
| PDB | External Database | Details |
|---|---|---|
| Ser 228 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28785.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 352.4 | |
| All* | Total formula weight | 29137.7 |
