9S6E

Cryo-EM structure of human caspase-9 CARD (H38R) mutant filament

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (B, A, C, D, E...)	Caspase-9	polymer	97	11303.9	16	UniProt (P55211) Pfam (PF00619)	Homo sapiens (human)	CASP-9,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3,APAF-3,ICE-like apoptotic protease 6,ICE-LAP6

Sequence modifications

B, A, C, D, E, F, G, H, I, J, K, L, M, N, O, P: 1 - 95 (UniProt: P55211)

PDB	External Database	Details
Ser -1	-	expression tag
Gly 0	-	expression tag
Arg 38	His 38	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	180862.4
All*	Total formula weight	180862.4

*Water molecules are not included.