9S4U
CgCdr1 in complex with Itraconazole, ATP and ADP-Mg
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Pleiotropic ABC efflux transporter of multiple drugs CDR1 | polymer | 1508 | 170594.5 | 1 | UniProt (Q6FK23) | Nakaseomyces glabratus | Pleiotropic drug resistance protein CDR1 |
| 2 | B (A) | LYSINE | non-polymer | 147.2 | 1 | Chemie (LYS) PubChem (641599) | |||
| 3 | C (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 5 | E (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 6 | F (A) | 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one | non-polymer | 705.6 | 1 | Chemie (1YN) PubChem (14179008) | |||
| 7 | G, H, I, J, K... (A) | ERGOSTEROL | non-polymer | 396.6 | 8 | Chemie (ERG) PubChem (444679) | |||
| 8 | O (A) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 1 - 1499 (UniProt: Q6FK23)
| PDB | External Database | Details |
|---|---|---|
| Gly 1500 | - | expression tag |
| Gly 1501 | - | expression tag |
| Arg 1502 | - | expression tag |
| His 1503 | - | expression tag |
| His 1504 | - | expression tag |
| His 1505 | - | expression tag |
| His 1506 | - | expression tag |
| His 1507 | - | expression tag |
| His 1508 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 170594.5 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 4984.7 | |
| All* | Total formula weight | 175579.2 |
