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9S4N

Activated-state RyR1 with activating ligand mixture (Calcium/ACP/Caffeine) in the native membrane

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Ryanodine receptor 1polymer5037565908.64UniProt (P11716)Oryctolagus cuniculus (rabbit)RYR-1,RyR1,Skeletal muscle calcium release channel,Skeletal muscle ryanodine receptor,Skeletal muscle-type ryanodine receptor,Type 1 ryanodine receptor
2E, F, G, H
(E, F, G, H)
Peptidyl-prolyl cis-trans isomerase FKBP1Apolymer10811967.74UniProt (P62943)Oryctolagus cuniculus (Rabbit)PPIase FKBP1A,12 kDa FK506-binding protein,12 kDa FKBP,FKBP-12,Calstabin-1,FK506-binding protein 1A,FKBP-1A,Immunophilin FKBP12,Rotamase
3BA, I, P, V
(D, A, B, C)
ZINC IONnon-polymer65.44Chemie (ZN)
PubChem (32051)
4CA, J, Q, W
(D, A, B, C)
CALCIUM IONnon-polymer40.14Chemie (CA)
PubChem (271)
5DA, K, R, X
(D, A, B, C)
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTERnon-polymer505.24Chemie (ACP)
6EA, L, S, Y
(D, A, B, C)
CAFFEINEnon-polymer194.24Chemie (CFF)
PubChem (2519)
7AA, FA, M, N, O...
(C, D, A, B)
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.18Chemie (POV)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight2311505.3
Non-Polymers*Number of molecules24
Total formula weight9300.2
All*Total formula weight2320805.5
*Water molecules are not included.

258009

PDB entries from 2026-08-12

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