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9S48

Human SIRT2 in Complex with RW-80

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
NAD-dependent protein deacetylase sirtuin-2polymer30234177.41UniProt (Q8IXJ6)
Pfam (PF02146)
Homo sapiens (human)NAD-dependent protein defatty-acylase sirtuin-2,Regulatory protein SIR2 homolog 2,SIR2-like protein 2
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
~{N}-[4-[[3-[2-(4,6-dimethylpyrimidin-2-yl)sulfanylethanoylamino]phenyl]methoxy]-2-iodanyl-phenyl]-1-methyl-pyrazole-4-carboxamidenon-polymer628.51Chemie (A1JLL)
4D, E, F, G, H...
(A)
1,2-ETHANEDIOLnon-polymer62.17Chemie (EDO)
5K
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
6L
(A)
waterwater18.0241Chemie (HOH)
Sequence modifications
A: 56 - 356 (UniProt: Q8IXJ6)
PDBExternal DatabaseDetails
Ser 55-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34177.4
Non-Polymers*Number of molecules10
Total formula weight1187.4
All*Total formula weight35364.8
*Water molecules are not included.

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PDB entries from 2025-12-10

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