Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Epidermal growth factor receptor | polymer | 324 | 36874.7 | 1 | UniProt (P00533) | Homo sapiens (human) | Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1 |
| 2 | B (A) | 2-[[4-[2-(dimethylamino)ethyl-methyl-amino]phenyl]amino]-5-ethenyl-8-phenyl-pyrido[2,3-d]pyrimidin-7-one | non-polymer | 440.5 | 1 | Chemie (A1JLU) | |||
| 3 | C (A) | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence modifications
A: 696 - 1019 (UniProt: P00533)
| PDB | External Database | Details |
|---|---|---|
| Met 790 | Thr 790 | variant |
| Ser 797 | Cys 797 | conflict |
| Arg 858 | Leu 858 | variant |
| Ala 865 | Glu 865 | conflict |
| Ala 866 | Glu 866 | conflict |
| Ala 867 | Lys 867 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36874.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 440.5 | |
| All* | Total formula weight | 37315.3 |
