9S2X
Crystal structure of the human RAGE ectodomain in complex with murine S100A6 mutant Y84C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Advanced glycosylation end product-specific receptor | polymer | 304 | 32680.3 | 1 | UniProt (Q15109) Pfam (PF08205) Pfam (PF13927) | Homo sapiens (human) | Receptor for advanced glycosylation end products |
| 2 | B (B) | Protein S100-A6 | polymer | 91 | 10132.7 | 1 | UniProt (P14069) Pfam (PF01023) | Mus musculus (house mouse) | 5B10,Calcyclin,Prolactin receptor-associated protein,S100 calcium-binding protein A6 |
| 3 | C, D, E, F, Q... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) PubChem (32051) | |||
| 4 | G, H, I, J (A) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) PubChem (312) | |||
| 5 | K, L, M, N (A) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) PubChem (175) | |||
| 6 | O, P (B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 7 | S (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 8 | T, U (A, B) | water | water | 18.0 | 205 | Chemie (HOH) |
Sequence modifications
A: 23 - 323 (UniProt: Q15109)
B: 1 - 89 (UniProt: P14069)
| PDB | External Database | Details |
|---|---|---|
| Gly 20 | - | expression tag |
| Ala 21 | - | expression tag |
| Met 22 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Cys 84 | Tyr 84 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42813.0 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 873.6 | |
| All* | Total formula weight | 43686.6 |
