9S19
WRN helicase in complex with ATPgS and ssDNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN | polymer | 427 | 48597.1 | 2 | UniProt (Q14191) Pfam (PF00270) Pfam (PF00271) Pfam (PF16124) | Homo sapiens (human) | DNA helicase,RecQ-like type 3,RecQ protein-like 2,Werner syndrome protein |
| 2 | C, D (C, D) | DNA (5'-D(P*TP*AP*CP*CP*C)-3') | polymer | 15 | 4576.0 | 2 | Homo sapiens | ||
| 3 | E, N (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) PubChem (32051) | |||
| 4 | F, S (A, B) | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 2 | Chemie (AGS) | |||
| 5 | G, H, I, J, K... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 11 | Chemie (EDO) | |||
| 6 | L, O (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) PubChem (679) | |||
| 7 | V, W, X, Y (A, B, C, D) | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
A, B: 517 - 941 (UniProt: Q14191)
| PDB | External Database | Details |
|---|---|---|
| Gly 515 | - | expression tag |
| Met 516 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 106346.1 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2016.3 | |
| All* | Total formula weight | 108362.4 |
