9S02
PYCR1 in complex with 3-(2-thiazolyl)propionic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Isoform 3 of Pyrroline-5-carboxylate reductase 1, mitochondrial | polymer | 342 | 36075.5 | 5 | UniProt (P32322) Pfam (PF03807) Pfam (PF14748) | Homo sapiens (human) | P5C reductase 1,P5CR 1 |
| 2 | AA, F, NA, Q, VA (C, A, D, B, E) | 3-(1,3-thiazol-2-yl)propanoic acid | non-polymer | 157.2 | 5 | Chemie (R9M) | |||
| 3 | AB, BA, CA, FA, G... (E, C, A, D, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 38 | Chemie (EDO) | |||
| 4 | DA, EA, J, SA, U (C, A, D, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 5 | Chemie (DMS) | |||
| 5 | BB, CB, DB, EB, FB (A, B, C, D, E) | water | water | 18.0 | 724 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 0 - 319 (UniProt: P32322)
| PDB | External Database | Details |
|---|---|---|
| Met -22 | - | initiating methionine |
| His -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| Ser -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Gly -13 | - | expression tag |
| Val -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Glu -7 | - | expression tag |
| Asn -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 180377.3 | |
| Non-Polymers* | Number of molecules | 48 |
| Total formula weight | 3535.2 | |
| All* | Total formula weight | 183912.5 |
