9RZD

State 3 MAP 2 SPT6 with SETD2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (D)	RNA polymerase II subunit D	polymer	142	16331.3	1	UniProt (A0A287ADR4) Pfam (PF03874)	Sus scrofa (pig)
2	B (G)	DNA-directed RNA polymerase II subunit RPB7	polymer	172	19314.3	1	UniProt (A0A4X1VKG7) Pfam (PF03876) Pfam (PF00575)	Sus scrofa (pig)
3	C (O)	Histone-lysine N-methyltransferase SETD2	polymer	1133	127887.3	1	UniProt (Q9BYW2) Pfam (PF17907) Pfam (PF00856) Pfam (PF00397) Pfam (PF08236)	Homo sapiens (human)	HIF-1,Huntingtin yeast partner B,Huntingtin-interacting protein 1,HIP-1,Huntingtin-interacting protein B,Lysine N-methyltransferase 3A,Protein-lysine N-methyltransferase SETD2,SET domain-containing protein 2,hSET2,p231HBP
4	D (Z)	Transcription elongation factor SPT5	polymer	1087	121145.5	1	UniProt (O00267) Pfam (PF11942) Pfam (PF03439) Pfam (PF00467)	Homo sapiens (human)	hSPT5,DRB sensitivity-inducing factor 160 kDa subunit,DSIF p160,DRB sensitivity-inducing factor large subunit,DSIF large subunit,Tat-cotransactivator 1 protein,Tat-CT1 protein
5	E (M)	Transcription elongation factor SPT6	polymer	1729	199603.0	1	UniProt (Q7KZ85) Pfam (PF00575) Pfam (PF14633) Pfam (PF14632) Pfam (PF14641) Pfam (PF22706) Pfam (PF14639) Pfam (PF14635) Pfam (PF17674)	Homo sapiens (Human)	hSPT6,Histone chaperone suppressor of Ty6,Tat-cotransactivator 2 protein,Tat-CT2 protein

Sequence modifications

O: 1435 - 2564 (UniProt: Q9BYW2)

PDB	External Database	Details
Ser 1432	-	expression tag
Asn 1433	-	expression tag
Ala 1434	-	expression tag
Leu 1962	Pro 1962	variant

M: 1 - 1726 (UniProt: Q7KZ85)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	484281.3
All*	Total formula weight	484281.3

*Water molecules are not included.