9RZC
State 3 MAP 1 SETD2 bound to distal H3 of upstream nucleosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (N) | Non-template DNA | polymer | 197 | 61155.9 | 1 | synthetic construct | ||
| 2 | B (O) | Histone-lysine N-methyltransferase SETD2 | polymer | 1133 | 127887.3 | 1 | UniProt (Q9BYW2) Pfam (PF17907) Pfam (PF00856) Pfam (PF00397) Pfam (PF08236) | Homo sapiens (human) | HIF-1,Huntingtin yeast partner B,Huntingtin-interacting protein 1,HIP-1,Huntingtin-interacting protein B,Lysine N-methyltransferase 3A,Protein-lysine N-methyltransferase SETD2,SET domain-containing protein 2,hSET2,p231HBP |
| 3 | C (T) | Template DNA | polymer | 197 | 60522.5 | 1 | synthetic construct | ||
| 4 | D, L (a, e) | Histone H3.2 | polymer | 136 | 15391.1 | 2 | UniProt (Q71DI3) Pfam (PF00125) | Homo sapiens (human) | H3-clustered histone 13,H3-clustered histone 14,H3-clustered histone 15,Histone H3/m,Histone H3/o |
| 5 | E, H (b, f) | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 6 | F, I (c, g) | Histone H2A type 1-B/E | polymer | 135 | 14721.1 | 2 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 7 | G, J (d, h) | Histone H2B type 1-K | polymer | 126 | 13921.2 | 2 | UniProt (O60814) Pfam (PF00125) | Homo sapiens (human) | H2B K,HIRA-interacting protein 1 |
| 8 | K (k) | FACT complex subunit SPT16 | polymer | 1049 | 120291.0 | 1 | UniProt (Q9Y5B9) Pfam (PF14826) Pfam (PF00557) Pfam (PF08644) Pfam (PF08512) Pfam (PF21091) | Homo sapiens (human) | Chromatin-specific transcription elongation factor 140 kDa subunit,FACT 140 kDa subunit,FACTp140,Facilitates chromatin transcription complex subunit SPT16,hSPT16 |
Sequence modifications
O: 1572 - 2701 (UniProt: Q9BYW2)
a, e: 0 - 135 (UniProt: Q71DI3)
c, g: 0 - 129 (UniProt: P04908)
k: 1 - 1047 (UniProt: Q9Y5B9)
| PDB | External Database | Details |
|---|---|---|
| Ser 1569 | - | expression tag |
| Asn 1570 | - | expression tag |
| Ala 1571 | - | expression tag |
| Leu 2099 | Pro 1962 | variant |
| PDB | External Database | Details |
|---|---|---|
| Met 36 | Lys 37 | engineered mutation |
| Ala 110 | Cys 111 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser -5 | - | expression tag |
| Asn -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Trp -1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Asn 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 480712.3 | |
| All* | Total formula weight | 480712.3 |
