9RXS
Structure of the PDZ4 domain from human PDZK1 (NHERF3) with the C-terminal residues (VLKSTQF) of human URAT1 transporter (SLC22A12)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Na(+)/H(+) exchange regulatory cofactor NHE-RF3,Solute carrier family 22 member 12 | polymer | 92 | 9924.4 | 2 | UniProt (Q5T2W1) UniProt (Q96S37) Pfam (PF00595) | Homo sapiens (human) | NHERF-3,CFTR-associated protein of 70 kDa,Na(+)/H(+) exchanger regulatory factor 3,Na/Pi cotransporter C-terminal-associated protein 1,NaPi-Cap1,PDZ domain-containing protein 1,Sodium-hydrogen exchanger regulatory factor 3,Organic anion transporter 4-like protein,Renal-specific transporter,RST,Urate anion exchanger 1,URAT1,Urate:anion antiporter SLC22A12 |
| 2 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A, B: 375 - 458 (UniProt: Q5T2W1)
A, B: 459 - 465 (UniProt: Q96S37)
| PDB | External Database | Details |
|---|---|---|
| Gly 374 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 19848.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 19940.9 |
