9RXI

Schistosoma mansoni Cathepsin D1 bound to Nb10C9

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Cathepsin D (A01 family)	polymer	381	41945.0	4	UniProt (G4VEV6) Pfam (PF07966) Pfam (PF00026)	Schistosoma mansoni
2	E, F (H, E)	Nb_10C9	polymer	152	16686.4	2		Lama glama
3	G, J (A, C)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	H, I, K, L (B, C, D)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
5	M, N, O, P, Q... (A, B, C, D, H...)	water	water		18.0	53	Chemie (HOH)

Sequence modifications

A, B, C, D: 15 - 385 (UniProt: G4VEV6)

PDB	External Database	Details
Glu 12	-	expression tag
Thr 13	-	expression tag
Gly 14	-	expression tag
Lys 386	-	expression tag
His 387	-	expression tag
His 388	-	expression tag
His 389	-	expression tag
His 390	-	expression tag
His 391	-	expression tag
His 392	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	201152.9
Non-Polymers*	Number of molecules	6
	Total formula weight	172.1
All*	Total formula weight	201325.0

*Water molecules are not included.