9RUR
Structure of WRN in complex with ATPgS and covalent ligand Compound 4d
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN | polymer | 427 | 48597.1 | 2 | UniProt (Q14191) Pfam (PF00270) Pfam (PF00271) Pfam (PF16124) | Homo sapiens (human) | DNA helicase,RecQ-like type 3,RecQ protein-like 2,Werner syndrome protein |
| 2 | C, N (A, B) | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 2 | Chemie (AGS) | |||
| 3 | D, E, J, P, Q (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 5 | Chemie (DMS) | |||
| 4 | F, G, K, L, O... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 5 | H (A) | 2-ethylsulfanyl-~{N}-[1-[(4-fluorophenyl)methyl]indazol-3-yl]ethanamide | non-polymer | 343.4 | 1 | Chemie (A1JJK) | |||
| 6 | I (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 7 | M, U (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 8 | V (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 9 | W, X (A, B) | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence modifications
A, B: 517 - 941 (UniProt: Q14191)
| PDB | External Database | Details |
|---|---|---|
| Gly 515 | - | expression tag |
| Met 516 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97194.1 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2859.4 | |
| All* | Total formula weight | 100053.6 |
