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9RUC

WT-HEK 80S ribosome bound to H2B mRNA (WT-H2B)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(L7)
5S rRNApolymer12038691.91GenBank (23898)Homo sapiens (human)
2B
(L8)
5.8S rRNApolymer15650157.71Homo sapiens
3C
(LA)
Large ribosomal subunit protein uL2polymer25427731.51UniProt (P62917)Homo sapiens (human)60S ribosomal protein L8
4D
(LB)
Large ribosomal subunit protein uL3polymer39645524.41UniProt (P39023)Homo sapiens (human)60S ribosomal protein L3,HIV-1 TAR RNA-binding protein B,TARBP-B
5E
(LC)
60S ribosomal protein L4polymer42747804.61UniProt (P36578)Homo sapiens (human)60S ribosomal protein L1,Large ribosomal subunit protein uL4
6F
(LD)
60S ribosomal protein L5polymer29734426.81UniProt (P46777)Homo sapiens (human)Large ribosomal subunit protein uL18
7G
(LE)
Large ribosomal subunit protein eL6polymer28832810.21UniProt (Q02878)Homo sapiens (human)60S ribosomal protein L6,Neoplasm-related protein C140,Tax-responsive enhancer element-binding protein 107,TaxREB107
8H
(LF)
Large ribosomal subunit protein uL30polymer24829291.01UniProt (P18124)Homo sapiens (human)60S ribosomal protein L7
9I
(LG)
60S ribosomal protein L7apolymer26630061.81UniProt (P62424)Homo sapiens (human)Large ribosomal subunit protein eL8,PLA-X polypeptide,Surfeit locus protein 3
10J
(LH)
Large ribosomal subunit protein uL6polymer18921584.21UniProt (P32969)Homo sapiens (human)60S ribosomal protein L9
11K
(LI)
Large ribosomal subunit protein uL16polymer21324543.01UniProt (P27635)Homo sapiens (human)60S ribosomal protein L10,Laminin receptor homolog,Protein QM,Ribosomal protein L10,Tumor suppressor QM
12L
(LJ)
60S ribosomal protein L11polymer17820288.51UniProt (P62913)Homo sapiens (human)CLL-associated antigen KW-12,Large ribosomal subunit protein uL5
13M
(LL)
Large ribosomal subunit protein eL13polymer21124321.71UniProt (P26373)Homo sapiens (human)60S ribosomal protein L13,Breast basic conserved protein 1
14N
(LM)
60S ribosomal protein L14polymer21523485.01UniProt (P50914)Homo sapiens (human)CAG-ISL 7,Large ribosomal subunit protein eL14
15O
(LN)
60S ribosomal protein L15polymer20424207.31UniProt (P61313)Homo sapiens (human)Large ribosomal subunit protein eL15
16P
(LO)
60S ribosomal protein L13apolymer20323633.41UniProt (P40429)Homo sapiens (human)23 kDa highly basic protein,Large ribosomal subunit protein uL13
17Q
(LP)
Large ribosomal subunit protein uL22polymer15417888.81UniProt (P18621)Homo sapiens (human)60S ribosomal protein L17,60S ribosomal protein L23,PD-1
18R
(LQ)
60S ribosomal protein L18polymer18821687.71UniProt (Q07020)Homo sapiens (human)Large ribosomal subunit protein eL18
19S
(LR)
60S ribosomal protein L19polymer19623535.31UniProt (P84098)Homo sapiens (human)Large ribosomal subunit protein eL19
20T
(LS)
60S ribosomal protein L18apolymer17620808.51UniProt (Q02543)Homo sapiens (human)Large ribosomal subunit protein eL20
21U
(LT)
60S ribosomal protein L21polymer16018610.01UniProt (P46778)Homo sapiens (human)Large ribosomal subunit protein eL21
22V
(LV)
60S ribosomal protein L23polymer14014892.51UniProt (P62829)Homo sapiens (human)60S ribosomal protein L17,Large ribosomal subunit protein uL14
23W
(LW)
60S ribosomal protein L24polymer15717825.11UniProt (P83731)Homo sapiens (human)60S ribosomal protein L30,Large ribosomal subunit protein eL24
24X
(LX)
60S ribosomal protein L23apolymer15617740.21UniProt (P62750)Homo sapiens (human)Large ribosomal subunit protein uL23
25Y
(LY)
60S ribosomal protein L26polymer14517303.41UniProt (P61254)Homo sapiens (human)Large ribosomal subunit protein uL24
26Z
(LZ)
60S ribosomal protein L27polymer13615835.81UniProt (P61353)Homo sapiens (human)Large ribosomal subunit protein eL27
27AA
(La)
Large ribosomal subunit protein uL15polymer14816619.51UniProt (P46776)Homo sapiens (human)
28BA
(Lb)
Large ribosomal subunit protein eL29polymer15917817.31UniProt (P47914)Homo sapiens (human)60S ribosomal protein L29,Cell surface heparin-binding protein HIP
29CA
(Lc)
60S ribosomal protein L30polymer11512805.11UniProt (P62888)Homo sapiens (human)Large ribosomal subunit protein eL30
30DA
(Ld)
60S ribosomal protein L31polymer12514494.91UniProt (P62899)Homo sapiens (human)Large ribosomal subunit protein eL31
31EA
(Le)
Large ribosomal subunit protein eL32polymer12915153.21UniProt (P62910)Homo sapiens (human)60S ribosomal protein L32
32FA
(Lf)
Large ribosomal subunit protein eL33polymer11012564.71UniProt (P18077)Homo sapiens (human)60S ribosomal protein L35a,Cell growth-inhibiting gene 33 protein
33GA
(Lg)
60S ribosomal protein L34polymer11713326.11UniProt (P49207)Homo sapiens (human)Large ribosomal subunit protein eL34
34HA
(Lh)
60S ribosomal protein L35polymer12314593.61UniProt (P42766)Homo sapiens (human)Large ribosomal subunit protein uL29
35IA
(Li)
60S ribosomal protein L36polymer10512290.91UniProt (Q9Y3U8)Homo sapiens (human)Large ribosomal subunit protein eL36
36JA
(Lj)
Large ribosomal subunit protein eL37polymer8710222.11UniProt (P61927)Homo sapiens (human)60S ribosomal protein L37,G1.16
37KA
(Lk)
60S ribosomal protein L38polymer708238.91UniProt (P63173)Homo sapiens (human)Large ribosomal subunit protein eL38
38LA
(Ll)
60S ribosomal protein L39polymer516426.81UniProt (P62891)Homo sapiens (human)Large ribosomal subunit protein eL39
39MA
(Lm)
Ubiquitin-ribosomal protein eL40 fusion proteinpolymer12714629.21UniProt (P62987)Homo sapiens (human)CEP52,Ubiquitin A-52 residue ribosomal protein fusion product 1
40NA
(Ln)
60S ribosomal protein L41polymer253473.51UniProt (P62945)Homo sapiens (human)HG12,Large ribosomal subunit protein eL41
41OA
(Lo)
Large ribosomal subunit protein eL42polymer10512329.81UniProt (P83881)Homo sapiens (human)60S ribosomal protein L36a,60S ribosomal protein L44,Cell growth-inhibiting gene 15 protein,Cell migration-inducing gene 6 protein
42PA
(Lp)
60S ribosomal protein L37apolymer9210299.41UniProt (P61513)Homo sapiens (human)Large ribosomal subunit protein eL43
43QA
(Lr)
Large ribosomal subunit protein eL28polymer13715679.51UniProt (P46779)Homo sapiens (human)60S ribosomal protein L28
44RA
(Pt)
P site tRNApolymer7724846.91GenBank (1870104878)Homo sapiens (human)
45SA
(SA)
Small ribosomal subunit protein uS2polymer29532778.81UniProt (A0A2J8WY29)Homo sapiens (human)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40
46TA
(SB)
40S ribosomal protein S3apolymer26430002.11UniProt (P61247)Homo sapiens (human)Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1
47UA
(SC)
40S ribosomal protein S2polymer29331376.51UniProt (P15880)Homo sapiens (human)40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5
48VA
(SF)
40S ribosomal protein S5polymer20422913.51UniProt (P46782)Homo sapiens (human)Small ribosomal subunit protein uS7
49WA
(SI)
40S ribosomal protein S8polymer20824263.41UniProt (P62241)Homo sapiens (human)Small ribosomal subunit protein eS8
50XA
(mR)
Histone H2B mRNApolymer278622.11Homo sapiens
51YA
(SD)
40S ribosomal protein S3polymer24326729.41UniProt (P23396)Homo sapiens (human)Small ribosomal subunit protein uS3
52ZA
(SE)
Small ribosomal subunit protein eS4, X isoformpolymer26329654.91UniProt (P62701)Homo sapiens (human)40S ribosomal protein S4,SCR10,Single copy abundant mRNA protein
53AB
(SH)
40S ribosomal protein S7polymer19422168.91UniProt (P62081)Homo sapiens (human)Small ribosomal subunit protein eS7
54BB
(SK)
40S ribosomal protein S10polymer16518933.81UniProt (P46783)Homo sapiens (human)Small ribosomal subunit protein eS10
55CB
(SL)
Small ribosomal subunit protein uS17polymer15818468.81UniProt (P62280)Homo sapiens (human)40S ribosomal protein S11
56DB
(SN)
40S ribosomal protein S13polymer15117259.41UniProt (P62277)Homo sapiens (human)Small ribosomal subunit protein uS15
57EB
(SO)
40S ribosomal protein S14polymer15116302.81UniProt (P62263)Homo sapiens (human)Small ribosomal subunit protein uS11
58FB
(SP)
40S ribosomal protein S15polymer14517076.21UniProt (P62841)Homo sapiens (human)RIG protein,Small ribosomal subunit protein uS19
59GB
(SQ)
40S ribosomal protein S16polymer14616477.41UniProt (P62249)Homo sapiens (human)Small ribosomal subunit protein uS9
60HB
(SR)
40S ribosomal protein S17polymer13515578.21UniProt (P08708)Homo sapiens (human)Small ribosomal subunit protein eS17
61IB
(SS)
40S ribosomal protein S18polymer15217759.81UniProt (P62269)Homo sapiens (human)Ke-3,Ke3,Small ribosomal subunit protein uS13
62JB
(ST)
40S ribosomal protein S19polymer14516091.61UniProt (P39019)Homo sapiens (human)Small ribosomal subunit protein eS19
63KB
(SU)
40S ribosomal protein S20polymer11913398.81UniProt (P60866)Homo sapiens (human)Small ribosomal subunit protein uS10
64LB
(SV)
Small ribosomal subunit protein eS21polymer849150.41UniProt (P63220)Homo sapiens (human)40S ribosomal protein S21
65MB
(SW)
40S ribosomal protein S15apolymer13014865.61UniProt (P62244)Homo sapiens (human)Small ribosomal subunit protein uS8
66NB
(SY)
40S ribosomal protein S24polymer13315463.31UniProt (P62847)Homo sapiens (human)Small ribosomal subunit protein eS24
67OB
(SX)
40S ribosomal protein S23polymer14315844.71UniProt (P62266)Homo sapiens (human)Small ribosomal subunit protein uS12
68PB
(Sb)
40S ribosomal protein S27polymer849480.21UniProt (P42677)Homo sapiens (human)Metallopan-stimulin 1,MPS-1,Small ribosomal subunit protein eS27
69QB
(Sc)
40S ribosomal protein S28polymer697855.11UniProt (P62857)Homo sapiens (human)Small ribosomal subunit protein eS28
70RB
(Sd)
40S ribosomal protein S29polymer566690.81UniProt (P62273)Homo sapiens (human)Small ribosomal subunit protein uS14
71SB
(Se)
Ubiquitin-like FUBI-ribosomal protein eS30 fusion proteinpolymer13314415.71UniProt (P62861)Homo sapiens (human)FAU ubiquitin like and ribosomal protein S30 fusion
72TB
(Sg)
Small ribosomal subunit protein RACK1polymer31735101.61UniProt (P63244)Homo sapiens (human)Cell proliferation-inducing gene 21 protein,Guanine nucleotide-binding protein subunit beta-2-like 1,Guanine nucleotide-binding protein subunit beta-like protein 12.3,Human lung cancer oncogene 7 protein,HLC-7,Receptor for activated C kinase,Receptor for activated C kinase 1,Receptor of activated protein C kinase 1
73UB
(S2)
18S rRNApolymer1869602752.91GenBank (151415227)Homo sapiens (human)
74VB
(L5)
28S rRNApolymer50691640802.51Homo sapiens
75WB
(Sa)
40S ribosomal protein S26polymer11513047.51UniProt (P62854)Homo sapiens (human)Small ribosomal subunit protein eS26
76XB
(S6)
E site tRNApolymer7724832.91GenBank (1870104878)Homo sapiens (human)
77YB
(SG)
40S ribosomal protein S6polymer24928751.91UniProt (P62753)Homo sapiens (human)Phosphoprotein NP33,Small ribosomal subunit protein eS6
78ZB
(LU)
60S ribosomal protein L22polymer12814813.01UniProt (P35268)Homo sapiens (human)EBER-associated protein,EAP,Epstein-Barr virus small RNA-associated protein,Heparin-binding protein HBp15,Large ribosomal subunit protein eL22
79AC
(SZ)
Small ribosomal subunit protein eS25polymer12513776.21UniProt (P62851)Homo sapiens (human)40S ribosomal protein S25
80BC
(SJ)
40S ribosomal protein S9polymer19422641.61UniProt (P46781)Homo sapiens (human)Small ribosomal subunit protein uS4
81AF, AG, AH, AI, AJ...
(L5, Lj, L7, L8, LA...)
MAGNESIUM IONnon-polymer24.3223Chemie (MG)
82AM, AN, BM, BN, CM...
(L5, SL, SO, L8, LA...)
POTASSIUM IONnon-polymer39.151Chemie (K)
83AE, BE, CE, DE, GN...
(S2, L5, LS, Le)
SODIUM IONnon-polymer23.08Chemie (NA)
84AD, CD, DD, ED, FD...
(Lg, Lj, Lm, Lo, Lp...)
ZINC IONnon-polymer65.46Chemie (ZN)
85JD
(S2)
HYGROMYCIN Bnon-polymer527.51Chemie (HYG)
86EE, FE, GE
(L5)
SPERMIDINEnon-polymer145.23Chemie (SPD)
87AO, AP, BO, BP, CO...
(LR, SE, LS, SL, LT...)
waterwater18.02837Chemie (HOH)
Sequence modifications
LA: 1 - 254 (UniProt: P62917)
PDBExternal DatabaseDetails
Lys 254Glu 254conflict
Lr: 2 - 137 (UniProt: P46779)
PDBExternal DatabaseDetails
Ace 2-acetylation
SA: 2 - 295 (UniProt: A0A2J8WY29)
PDBExternal DatabaseDetails
Ace 1-acetylation
SV: 1 - 83 (UniProt: P63220)
PDBExternal DatabaseDetails
Ace 0-acetylation
Sg: 1 - 317 (UniProt: P63244)
PDBExternal DatabaseDetails
Asn 56Gln 56conflict
S2: 1 - 1869 (GenBank: 151415227)
PDBExternal DatabaseDetails
C 140U 126070conflict
A 338G 126268conflict
C 582U 126512conflict
C 583A 126513conflict
G 584A 126514conflict
U 1095C 127025conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains80
Total formula weight3806643.5
Non-Polymers*Number of molecules292
Total formula weight8953.6
All*Total formula weight3815597.1
*Water molecules are not included.

253389

PDB entries from 2026-05-13

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