9RTD

Crystal structure of DNA aptamer C8N5t in complex with Plasmodium falciparum lactate dehydrogenase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	L-lactate dehydrogenase	polymer	329	35843.5	4	UniProt (Q27743)	Plasmodium falciparum (malaria parasite P. falciparum)	LDH-P
2	E (G)	DNA (32-MER)	polymer	40	12367.0	1		synthetic construct
3	F, G, H, I, J (A, B, C, D, G)	water	water		18.0	166	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 316 (UniProt: Q27743)

PDB	External Database	Details
Met -12	-	initiating methionine
Ala -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
Glu -4	-	expression tag
Asn -3	-	expression tag
Leu -2	-	expression tag
Tyr -1	-	expression tag
Phe 0	-	expression tag
Gln 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	155741.0
All*	Total formula weight	155741.0

*Water molecules are not included.