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9RSQ

Cryo-EM structure of the Target of Rapamycin Complex 2 (TORC2) with the Avo1 PH domain (monomer)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase TOR2polymer2474281915.41UniProt (P32600)Saccharomyces cerevisiae (brewer's yeast)Dominant rapamycin resistance protein 2,Phosphatidylinositol 4-kinase TOR2,PI4-kinase TOR2,PI4K TOR2,PtdIns-4-kinase TOR2,Target of rapamycin kinase 2,Temperature-sensitive CSG2 suppressor protein 14
2B
(B)
Target of rapamycin complex subunit LST8polymer30334077.91UniProt (P41318)Saccharomyces cerevisiae (brewer's yeast)TORC subunit LST8,Lethal with SEC13 protein 8
3C, G
(C, H)
Target of rapamycin complex 2 subunit TSC11polymer1430164580.62UniProt (P40061)Saccharomyces cerevisiae (brewer's yeast)TORC2 subunit TSC11,Adheres voraciously to TOR2 protein 3,Temperature-sensitive CSG2 suppressor protein 11
4D
(D)
Target of rapamycin complex 2 subunit AVO2polymer42647206.51UniProt (Q04749)Saccharomyces cerevisiae (brewer's yeast)TORC2 subunit AVO2,Adheres voraciously to TOR2 protein 2
5E
(E)
Target of rapamycin complex 2 subunit BIT61polymer54360908.71UniProt (P47041)Saccharomyces cerevisiae (brewer's yeast)TORC2 subunit BIT61,61 kDa binding partner of TOR2 protein
6F
(G)
Target of rapamycin complex 2 subunit AVO1polymer1176131565.51UniProt (Q08236)Saccharomyces cerevisiae (brewer's yeast)TORC2 subunit AVO1,Adheres voraciously to TOR2 protein 1
7H
(A)
INOSITOL HEXAKISPHOSPHATEnon-polymer660.01Chemie (IHP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains7
Total formula weight884835.1
Non-Polymers*Number of molecules1
Total formula weight660.0
All*Total formula weight885495.2
*Water molecules are not included.

253389

PDB entries from 2026-05-13

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