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9RSJ

Cryo-EM structure of MATE transporter NorM-VC in complex with doxorubicin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Multidrug resistance protein NorMpolymer46149892.31UniProt (C3LML9)Vibrio choleraeMultidrug-efflux transporter,Na(+)/drug antiporter
2B
(H)
NabFab HCpolymer23925684.51synthetic construct
3C
(L)
NabFab LCpolymer21523258.81synthetic construct
4D
(N)
NorM-Nb17_4polymer13214357.01synthetic construct
5E
(K)
Anti-Fab nanobodypolymer12313390.61Lama glama
6F
(A)
DOXORUBICINnon-polymer543.51Chemie (DM2)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight126583.2
Non-Polymers*Number of molecules1
Total formula weight543.5
All*Total formula weight127126.7
*Water molecules are not included.

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PDB entries from 2026-01-14

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