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9RRO

Human TRPC5 in complex with (-) englerin A, full occupancy, intermediary desensitized state

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Short transient receptor potential channel 5polymer76589009.84UniProt (Q9UL62)Homo sapiens (human)TrpC5,Transient receptor protein 5,TRP-5,hTRP-5,hTRP5
2E, K, O, T
(A, B, C, D)
CALCIUM IONnon-polymer40.14Chemie (CA)
3F, L, P, U
(A, B, C, D)
ZINC IONnon-polymer65.44Chemie (ZN)
4G, M, Q, V
(A, B, C, D)
PHOSPHATIDYLETHANOLAMINEnon-polymer734.04Chemie (PTY)
5H, J, R, W
(A, C, D)
CHOLESTEROL HEMISUCCINATEnon-polymer486.74Chemie (Y01)
6I, N, S, X
(A, B, C, D)
(-)-englerin Anon-polymer442.54Chemie (A1L55)
Sequence modifications
A, B, C, D: 1 - 765 (UniProt: Q9UL62)
PDBExternal DatabaseDetails
Met 455Val 455conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight356039.3
Non-Polymers*Number of molecules20
Total formula weight7075.2
All*Total formula weight363114.5
*Water molecules are not included.

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PDB entries from 2026-05-13

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