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9RQQ

Tankyrase 2 in complex with an inhibitor

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Poly [ADP-ribose] polymerase tankyrase-2polymer21824771.01UniProt (Q9H2K2)
Pfam (PF00644)
Homo sapiens (human)ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,Protein poly-ADP-ribosyltransferase tankyrase-2,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-2,TANK2,Tankyrase-like protein,Tankyrase-related protein
2B
(A)
3-[(4-ethylphenyl)methyl]-7-fluoranyl-4~{H}-[1,2,3]triazolo[4,5-c]isoquinolin-5-onenon-polymer322.31Chemie (A1JIF)
3C
(A)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
4D
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
5E, F
(A)
SULFATE IONnon-polymer96.12Chemie (SO4)
6G
(A)
waterwater18.098Chemie (HOH)
Sequence modifications
A: 946 - 1161 (UniProt: Q9H2K2)
PDBExternal DatabaseDetails
Ser 944-expression tag
Met 945-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight24771.0
Non-Polymers*Number of molecules5
Total formula weight686.0
All*Total formula weight25457.0
*Water molecules are not included.

250835

PDB entries from 2026-03-18

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