9RP6
Crystal structure of covalent PDE6delta adduct modified by compound 13b
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | polymer | 156 | 18269.9 | 1 | UniProt (O43924) Pfam (PF05351) | Homo sapiens (human) | GMP-PDE delta,Protein p17 |
| 2 | B (A) | 4-[3,4-dimethyl-2-(4-methylphenyl)-7-oxidanylidene-pyrazolo[3,4-d]pyridazin-6-yl]-~{N}-(piperidin-4-ylmethyl)-~{N}-[(2,5,6-trimethylpyridin-3-yl)methyl]butane-1-sulfonamide | non-polymer | 619.8 | 1 | Chemie (A1JIC) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 4 | D (A) | water | water | 18.0 | 78 | Chemie (HOH) |
Sequence modifications
A: 1 - 150 (UniProt: O43924)
| PDB | External Database | Details |
|---|---|---|
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18269.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 711.9 | |
| All* | Total formula weight | 18981.8 |
