9ROH

Human alpha3 Na+,K+-ATPase in the Na+-occluded E2P state obtained under turnover conditions

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Sodium/potassium-transporting ATPase subunit alpha-3	polymer	1013	111944.3	1	UniProt (P13637)	Homo sapiens (human)	Na(+)/K(+) ATPase alpha-3 subunit,Na(+)/K(+) ATPase alpha(III) subunit,Sodium pump subunit alpha-3
2	B (B)	Sodium/potassium-transporting ATPase subunit beta-1	polymer	319	37232.6	1	UniProt (P05026)	Homo sapiens (human)	Sodium/potassium-dependent ATPase subunit beta-1
3	C (C)	Phospholemman	polymer	76	8755.0	1	UniProt (O00168)	Homo sapiens (human)	FXYD domain-containing ion transport regulator 1,Sodium/potassium-transporting ATPase subunit FXYD1
4	D, E, H (A, B)	CHOLESTEROL	non-polymer		386.7	3	Chemie (CLR) PubChem (5997)
5	F, G (A)	SODIUM ION	non-polymer		23.0	2	Chemie (NA) PubChem (923)
6	I, J, K (B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG) PubChem (24139)

Sequence modifications

B: 3 - 303 (UniProt: P05026)

PDB	External Database	Details
Met -15	-	initiating methionine
Ala -14	-	expression tag
Arg -13	-	expression tag
Ser -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Pro -1	-	expression tag
Arg 0	-	expression tag
Arg 1	-	expression tag
Ser 2	-	expression tag

C: 19 - 92 (UniProt: O00168)

PDB	External Database	Details
Gly 17	-	expression tag
Thr 18	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	157931.8
Non-Polymers*	Number of molecules	8
	Total formula weight	1869.6
All*	Total formula weight	159801.4

*Water molecules are not included.