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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9RN1

Structure of BAF-nucleosome complex with OCT4-SOX2 at SHL+6 in ADP-bound state, BAF47 bound to ATPase lobe 2

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(A, E)		Histone H3.1polymer13915719.42UniProt (P68431)Homo sapiens (human)Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
2B, F
(B, F)		Histone H4polymer10611676.72UniProt (P62805)Homo sapiens (human)
3C, G
(C, G)		Histone H2A type 1-B/Epolymer13314447.82UniProt (P04908)Homo sapiens (human)Histone H2A.2,Histone H2A/a,Histone H2A/m
4D, H
(D, H)		Histone H2B type 1-Jpolymer12814088.32UniProt (P06899)Homo sapiens (human)Histone H2B.1,Histone H2B.r,H2B/r
5I
(I)		Transcription activator BRG1polymer1647184923.81UniProt (P51532)Homo sapiens (human)ATP-dependent helicase SMARCA4,BRG1-associated factor 190A,BAF190A,Mitotic growth and transcription activator,Protein BRG-1,Protein brahma homolog 1,SNF2-beta,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
6J
(J)		Actin-like protein 6Apolymer42947509.81UniProt (O96019)Homo sapiens (human)53 kDa BRG1-associated factor A,Actin-related protein Baf53a,ArpNbeta,BRG1-associated factor 53A,BAF53A,INO80 complex subunit K
7K
(K)		Actin, cytoplasmic 1, N-terminally processedpolymer37541782.71UniProt (P60709)Homo sapiens (human)
8L
(L)		AT-rich interactive domain-containing protein 1Apolymer2285242250.31UniProt (O14497)Homo sapiens (human)ARID domain-containing protein 1A,B120,BRG1-associated factor 250,BAF250,BRG1-associated factor 250a,BAF250A,Osa homolog 1,hOSA1,SWI-like protein,SWI/SNF complex protein p270,SWI/SNF-related,matrix-associated,actin-dependent regulator of chromatin subfamily F member 1,hELD
9M
(M)		SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1polymer38544199.21UniProt (Q12824)Homo sapiens (human)BRG1-associated factor 47,BAF47,Integrase interactor 1 protein,SNF5 homolog,hSNF5
10N, O
(N, O)		SWI/SNF complex subunit SMARCC2polymer1214133048.12UniProt (Q8TAQ2)Homo sapiens (human)BRG1-associated factor 170,BAF170,SWI/SNF complex 170 kDa subunit,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2
11P
(P)		SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1polymer51558311.41UniProt (Q96GM5)Homo sapiens (human)60 kDa BRG-1/Brm-associated factor subunit A,BRG1-associated factor 60A,BAF60A,SWI/SNF complex 60 kDa subunit
12Q
(Q)		SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1polymer41146710.41UniProt (Q969G3)Homo sapiens (human)BRG1-associated factor 57,BAF57
13R
(R)		Zinc finger protein ubi-d4polymer43548554.11UniProt (Q92785)Homo sapiens (human)Apoptosis response zinc finger protein,BRG1-associated factor 45D,BAF45D,D4,zinc and double PHD fingers family 2,Protein requiem
14S
(V)		Green fluorescent protein,POU domain, class 5, transcription factor 1polymer64570735.51UniProt (P42212)
UniProt (Q01860)		Aequorea victoriaOctamer-binding protein 3,Oct-3,Octamer-binding protein 4,Oct-4,Octamer-binding transcription factor 3,OTF-3
15T
(W)		Transcription factor SOX-2polymer10512718.71UniProt (P48431)Homo sapiens (human)
16U
(X)		DNA (148-MER)polymer22769794.41synthetic construct
17V
(Y)		DNA (148-MER)polymer22770389.81synthetic construct
Sequence modifications
A, E: 1 - 136 (UniProt: P68431)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
B, F: 1 - 103 (UniProt: P62805)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
C, G: 1 - 130 (UniProt: P04908)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
D, H: 1 - 125 (UniProt: P06899)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
R: 1 - 391 (UniProt: Q92785)
PDBExternal DatabaseDetails
Gly 392-expression tag
Thr 393-expression tag
Leu 394-expression tag
Glu 395-expression tag
Val 396-expression tag
Leu 397-expression tag
Phe 398-expression tag
Gln 399-expression tag
Gly 400-expression tag
Pro 401-expression tag
Gly 402-expression tag
Gly 403-expression tag
Ser 404-expression tag
Gly 405-expression tag
Ser 406-expression tag
Ala 407-expression tag
Trp 408-expression tag
Ser 409-expression tag
His 410-expression tag
Pro 411-expression tag
Gln 412-expression tag
Phe 413-expression tag
Glu 414-expression tag
Lys 415-expression tag
Gly 416-expression tag
Gly 417-expression tag
Gly 418-expression tag
Ser 419-expression tag
Gly 420-expression tag
Gly 421-expression tag
Gly 422-expression tag
Ser 423-expression tag
Gly 424-expression tag
Gly 425-expression tag
Ser 426-expression tag
Ala 427-expression tag
Trp 428-expression tag
Ser 429-expression tag
His 430-expression tag
Pro 431-expression tag
Gln 432-expression tag
Phe 433-expression tag
Glu 434-expression tag
Lys 435-expression tag
V: -246 - -10 (UniProt: P42212)
PDBExternal DatabaseDetails
Met -272-initiating methionine
Asp -271-expression tag
Trp -270-expression tag
Ser -269-expression tag
His -268-expression tag
Pro -267-expression tag
Gln -266-expression tag
Phe -265-expression tag
Glu -264-expression tag
Lys -263-expression tag
Ser -262-expression tag
Ala -261-expression tag
Val -260-expression tag
Asp -259-expression tag
Glu -258-expression tag
Asn -257-expression tag
Leu -256-expression tag
Tyr -255-expression tag
Phe -254-expression tag
Gln -253-expression tag
Gly -252-expression tag
Gly -251-expression tag
Gly -250-expression tag
Arg -249-expression tag
Met -248-expression tag
Val -247-expression tag
Leu -184Phe 64conflict
Thr -183Ser 65conflict
Lys -42Ala 206conflict
Leu -17His 231conflict
Glu -9-linker
Ala -8-linker
Ala -7-linker
Ala -6-linker
Lys -5-linker
Glu -4-linker
Ala -3-linker
Ala -2-linker
Ala -1-linker
Lys 0-linker
V: 1 - 360 (UniProt: Q01860)
PDBExternal DatabaseDetails
Leu 361-expression tag
Pro 362-expression tag
Glu 363-expression tag
Thr 364-expression tag
Gly 365-expression tag
Gly 366-expression tag
His 367-expression tag
His 368-expression tag
His 369-expression tag
His 370-expression tag
His 371-expression tag
His 372-expression tag
W: 37 - 118 (UniProt: P48431)
PDBExternal DatabaseDetails
Met 14-initiating methionine
Asp 15-expression tag
Trp 16-expression tag
Ser 17-expression tag
His 18-expression tag
Pro 19-expression tag
Gln 20-expression tag
Phe 21-expression tag
Glu 22-expression tag
Lys 23-expression tag
Ser 24-expression tag
Ala 25-expression tag
Val 26-expression tag
Asp 27-expression tag
Glu 28-expression tag
Asn 29-expression tag
Leu 30-expression tag
Tyr 31-expression tag
Phe 32-expression tag
Gln 33-expression tag
Gly 34-expression tag
Gly 35-expression tag
Met 36-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains22
Total formula weight1315840.9
All*Total formula weight1315840.9
*Water molecules are not included.

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PDB entries from 2026-02-11

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