9RMW
GluA4 in complex with TARP-2, open state, structure of TMD/LBD domains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, F, G (A, B, C, D) | Isoform 2 of Glutamate receptor 4 | polymer | 882 | 98671.9 | 4 | UniProt (P19493) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR-4,GluR4,AMPA-selective glutamate receptor 4,GluR-D,Glutamate receptor ionotropic,AMPA 4,GluA4 |
| 2 | C, D, E, H (E, F, G, H) | Voltage-dependent calcium channel gamma-2 subunit | polymer | 323 | 35950.8 | 4 | UniProt (Q71RJ2) Pfam (PF00822) | Rattus norvegicus (Norway rat) | Neuronal voltage-gated calcium channel gamma-2 subunit,Stargazin,Transmembrane AMPAR regulatory protein gamma-2,TARP gamma-2 |
| 3 | DA, FA, GA, HA, I... (D, A, H, B, E...) | PALMITIC ACID | non-polymer | 256.4 | 18 | Chemie (PLM) | |||
| 4 | EA, K (D, A) | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 2 | Chemie (OLC) PubChem (25021708) PubChem (46840179) PubChem (54294271) PubChem (54294270) PubChem (33022) PubChem (5283468) PubChem (5364833) PubChem (11451146) PubChem (12178130) | |||
| 5 | AA, JA, L, S (C, D, A, B) | CYCLOTHIAZIDE | non-polymer | 389.9 | 4 | Chemie (CYZ) PubChem (2910) PubChem (21550932) PubChem (177678892) PubChem (44582559) PubChem (52949708) PubChem (657321) PubChem (5288009) PubChem (92142359) PubChem (98047041) PubChem (101691639) PubChem (5388988) PubChem (92143401) PubChem (92215537) PubChem (6603794) PubChem (98047042) PubChem (101691640) PubChem (11972587) PubChem (131842006) | |||
| 6 | CA, IA, N, R (C, D, A, B) | GLUTAMIC ACID | non-polymer | 147.1 | 4 | Chemie (GLU) PubChem (611) PubChem (23327) PubChem (33032) | |||
| 7 | BA (C) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) | |||
| 8 | LA, MA, NA, OA (A, B, C, D) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 21 - 902 (UniProt: P19493)
E, F, G, H: 1 - 323 (UniProt: Q71RJ2)
| PDB | External Database | Details |
|---|---|---|
| Ile 734 | Thr 734 | variant |
| PDB | External Database | Details |
|---|---|---|
| Ile 14 | Thr 14 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 538491.0 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 7516.8 | |
| All* | Total formula weight | 546007.8 |
