9RMW
GluA4 in complex with TARP-2, open state, structure of TMD/LBD domains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, F, G (A, B, C, D) | Isoform 2 of Glutamate receptor 4 | polymer | 882 | 98671.9 | 4 | UniProt (P19493) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR-4,GluR4,AMPA-selective glutamate receptor 4,GluR-D,Glutamate receptor ionotropic,AMPA 4,GluA4 |
| 2 | C, D, E, H (E, F, G, H) | Voltage-dependent calcium channel gamma-2 subunit | polymer | 323 | 35950.8 | 4 | UniProt (Q71RJ2) Pfam (PF00822) | Rattus norvegicus (Norway rat) | Neuronal voltage-gated calcium channel gamma-2 subunit,Stargazin,Transmembrane AMPAR regulatory protein gamma-2,TARP gamma-2 |
| 3 | DA, FA, GA, HA, I... (D, A, H, B, E...) | PALMITIC ACID | non-polymer | 256.4 | 18 | Chemie (PLM) | |||
| 4 | EA, K (D, A) | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 2 | Chemie (OLC) | |||
| 5 | AA, JA, L, S (C, D, A, B) | CYCLOTHIAZIDE | non-polymer | 389.9 | 4 | Chemie (CYZ) | |||
| 6 | CA, IA, N, R (C, D, A, B) | GLUTAMIC ACID | non-polymer | 147.1 | 4 | Chemie (GLU) | |||
| 7 | BA (C) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 8 | LA, MA, NA, OA (A, B, C, D) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 21 - 902 (UniProt: P19493)
E, F, G, H: 1 - 323 (UniProt: Q71RJ2)
| PDB | External Database | Details |
|---|---|---|
| Ile 734 | Thr 734 | variant |
| PDB | External Database | Details |
|---|---|---|
| Ile 14 | Thr 14 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 538491.0 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 7516.8 | |
| All* | Total formula weight | 546007.8 |
