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9RLM

HUMAN CYCLOPHILIN D IN COMPLEX WITH INHIBITOR

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Peptidyl-prolyl cis-trans isomerase F, mitochondrialpolymer16417652.11UniProt (P30405)
Pfam (PF00160)
Homo sapiens (human)PPIase F,Cyclophilin D,CypD,Cyclophilin F,Mitochondrial cyclophilin,CyP-M,Rotamase F
2B
(A)
~{N}'-cyclopentyl-~{N}-[2-[(1~{R},9~{R},10~{S})-10-oxidanyl-12-oxa-8-azatricyclo[7.3.1.0^{2,7}]trideca-2(7),3,5-trien-4-yl]ethyl]ethanediamidenon-polymer373.41Chemie (A1JG4)
3C
(A)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
4D
(A)
TETRAETHYLENE GLYCOLnon-polymer194.21Chemie (PG4)
5E
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
6F
(A)
waterwater18.0216Chemie (HOH)
Sequence modifications
A: 44 - 207 (UniProt: P30405)
PDBExternal DatabaseDetails
Ile 175Lys 175engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight17652.1
Non-Polymers*Number of molecules4
Total formula weight813.9
All*Total formula weight18466.0
*Water molecules are not included.

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PDB entries from 2025-12-10

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