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9REL

Crystal Structure of the Protein-Kinase A catalytic subunit from Cricetulus griseus in complex with F283

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
cAMP-dependent protein kinase catalytic subunit alphapolymer35341113.81UniProt (P25321)Cricetulus griseus (Chinese hamster)PKA C-alpha
2B
(A)
PENTAETHYLENE GLYCOLnon-polymer238.31Chemie (1PE)
3C, D
(A)
4-(2-{[methyl(prop-2-yn-1-yl)amino]methyl}-1,3-thiazol-4-yl)piperidin-4-olnon-polymer265.42Chemie (D8V)
4E, F, G, H, I
(A)
DIMETHYL SULFOXIDEnon-polymer78.15Chemie (DMS)
5J
(A)
waterwater18.0283Chemie (HOH)
Sequence modifications
A: 0 - 350 (UniProt: P25321)
PDBExternal DatabaseDetails
Gly -2-expression tag
His -1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41113.8
Non-Polymers*Number of molecules8
Total formula weight1159.7
All*Total formula weight42273.5
*Water molecules are not included.

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PDB entries from 2026-02-11

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