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9REK

Crystal Structure of the Protein-Kinase A catalytic subunit from Cricetulus griseus in complex with F274

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
cAMP-dependent protein kinase catalytic subunit alphapolymer35341113.81UniProt (P25321)Cricetulus griseus (Chinese hamster)PKA C-alpha
2B, C, D, E
(A)
[(2S)-1,9-dimethyl-1,2,3,4,5,6-hexahydropyrido[2,3-b][1,5]diazocin-2-yl]methanolnon-polymer221.34Chemie (D8P)
3F, G, H, I, J...
(A)
DIMETHYL SULFOXIDEnon-polymer78.16Chemie (DMS)
4L
(A)
waterwater18.0252Chemie (HOH)
Sequence modifications
A: 0 - 350 (UniProt: P25321)
PDBExternal DatabaseDetails
Gly -2-expression tag
His -1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41113.8
Non-Polymers*Number of molecules10
Total formula weight1354.0
All*Total formula weight42467.8
*Water molecules are not included.

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PDB entries from 2026-02-18

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