9RCI
Crystal Structure of Flap Endonuclease FEN1 with Compound 28
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Flap endonuclease 1 | polymer | 342 | 38642.4 | 2 | UniProt (P39748) Pfam (PF00752) Pfam (PF00867) | Homo sapiens (human) | FEN-1,DNase IV,Flap structure-specific endonuclease 1,Maturation factor 1,MF1,hFEN-1 |
| 2 | C, D, G, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | E, I (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | F, J (A, B) | (3~{S})-13-[(1~{S})-1-(2-methylquinolin-7-yl)ethoxy]-11-oxidanyl-5-oxa-1,8-diazatricyclo[8.4.0.0^{3,8}]tetradeca-10,13-diene-9,12-dione | non-polymer | 421.4 | 2 | Chemie (A1JD4) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 336 (UniProt: P39748)
| PDB | External Database | Details |
|---|---|---|
| Leu 337 | - | expression tag |
| Glu 338 | - | expression tag |
| Val 339 | - | expression tag |
| Leu 340 | - | expression tag |
| Phe 341 | - | expression tag |
| Gln 342 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77284.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1064.2 | |
| All* | Total formula weight | 78349.0 |
