9RCG
Vitamin D receptor complex with a vitamin D receptor agonist/histone deacetylase inhibitor hybrid molecule
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Vitamin D3 receptor A | polymer | 302 | 34060.7 | 1 | UniProt (Q9PTN2) Pfam (PF00104) | Danio rerio (zebrafish) | VDR-A,1,25-dihydroxyvitamin D3 receptor A,Nuclear receptor subfamily 1 group I member 1-A |
| 2 | B (B) | Nuclear receptor coactivator 2 | polymer | 13 | 1579.9 | 1 | UniProt (Q15596) | Homo sapiens | NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2 |
| 3 | C (A) | 4-[4-[3-[5-[(3~{S})-4,4-dimethyl-3-oxidanyl-pentyl]-4-methyl-1,3-thiazol-2-yl]pentan-3-yl]phenoxy]-~{N}-oxidanyl-butanamide | non-polymer | 476.7 | 1 | Chemie (A1JD5) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 169 | Chemie (HOH) |
Sequence modifications
A: 156 - 453 (UniProt: Q9PTN2)
| PDB | External Database | Details |
|---|---|---|
| Gly 152 | - | expression tag |
| Ser 153 | - | expression tag |
| His 154 | - | expression tag |
| Met 155 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35640.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 476.7 | |
| All* | Total formula weight | 36117.2 |
