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9R9J

IRAK4 in complex with inhibitor

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Interleukin-1 receptor-associated kinase 4polymer30834635.04UniProt (Q9NWZ3)
Pfam (PF07714)
Homo sapiens (human)IRAK-4,Renal carcinoma antigen NY-REN-64
2E, F, G, H
(A, B, C, D)
~{N}-[2-(3-methyl-3-oxidanyl-butyl)-6-(2-oxidanylpropan-2-yl)indazol-5-yl]-1-(2-methylpyridin-4-yl)pyrazole-3-carboxamidenon-polymer462.54Chemie (A1JDR)
3I, J, K, L
(A, B, C, D)
waterwater18.0442Chemie (HOH)
Sequence modifications
A, B, C, D: 154 - 460 (UniProt: Q9NWZ3)
PDBExternal DatabaseDetails
Gly 153-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight138540.0
Non-Polymers*Number of molecules4
Total formula weight1850.2
All*Total formula weight140390.2
*Water molecules are not included.

250059

PDB entries from 2026-03-04

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