9R8Y
Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Carbonic anhydrase 9 | polymer | 256 | 28089.6 | 4 | UniProt (Q16790) Pfam (PF00194) | Homo sapiens (human) | Carbonate dehydratase IX,Carbonic anhydrase IX,CA-IX,CAIX,Membrane antigen MN,P54/58N,Renal cell carcinoma-associated antigen G250,RCC-associated antigen G250,pMW1 |
| 2 | E, G, I, K (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F, H, J, L (A, B, C, D) | ~{N}-butyl-4-cyclohexylsulfanyl-3-sulfamoyl-benzamide | non-polymer | 370.5 | 4 | Chemie (A1JDL) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 691 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 4 - 258 (UniProt: Q16790)
| PDB | External Database | Details |
|---|---|---|
| Gly 3 | - | expression tag |
| Ser 41 | Cys 174 | engineered mutation |
| Gln 213 | Asn 346 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 112358.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1743.8 | |
| All* | Total formula weight | 114102.1 |
