9R8N
Structure of human NHE6.1 bound to PIP2 (core-TM domain)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Isoform 2 of Sodium/hydrogen exchanger 6 | polymer | 772 | 85507.8 | 2 | UniProt (Q92581) Pfam (PF00999) | Homo sapiens (human) | Na(+)/H(+) exchanger 6,NHE-6,Solute carrier family 9 member 6 |
| 2 | C, I (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 3 | D, E, J, K (A, B) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 4 | Chemie (LMT) PubChem (114880) | |||
| 4 | F, L (A, B) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 2 | Chemie (PC1) | |||
| 5 | G, M (A, B) | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE | non-polymer | 734.0 | 2 | Chemie (PCF) | |||
| 6 | H, N (A, B) | Dipalmitoyl Phosphatidylinositol 3,5-bisphosphate | non-polymer | 971.0 | 2 | Chemie (A1JDN) | |||
| 7 | O, P (A, B) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 701 (UniProt: Q92581)
| PDB | External Database | Details |
|---|---|---|
| Asp 702 | - | expression tag |
| Pro 703 | - | expression tag |
| Ala 704 | - | expression tag |
| Phe 705 | - | expression tag |
| Leu 706 | - | expression tag |
| Tyr 707 | - | expression tag |
| Lys 708 | - | expression tag |
| Val 709 | - | expression tag |
| Val 710 | - | expression tag |
| Asp 711 | - | expression tag |
| Ile 712 | - | expression tag |
| Lys 713 | - | expression tag |
| Ala 714 | - | expression tag |
| Ala 715 | - | expression tag |
| Asp 716 | - | expression tag |
| Ile 717 | - | expression tag |
| Thr 718 | - | expression tag |
| Ser 719 | - | expression tag |
| Leu 720 | - | expression tag |
| Tyr 721 | - | expression tag |
| Lys 722 | - | expression tag |
| Lys 723 | - | expression tag |
| Val 724 | - | expression tag |
| Gly 725 | - | expression tag |
| Trp 726 | - | expression tag |
| Ser 727 | - | expression tag |
| His 728 | - | expression tag |
| Pro 729 | - | expression tag |
| Gln 730 | - | expression tag |
| Phe 731 | - | expression tag |
| Glu 732 | - | expression tag |
| Lys 733 | - | expression tag |
| Gly 734 | - | expression tag |
| Gly 735 | - | expression tag |
| Gly 736 | - | expression tag |
| Ser 737 | - | expression tag |
| Gly 738 | - | expression tag |
| Gly 739 | - | expression tag |
| Gly 740 | - | expression tag |
| Ser 741 | - | expression tag |
| Gly 742 | - | expression tag |
| Gly 743 | - | expression tag |
| Gly 744 | - | expression tag |
| Ser 745 | - | expression tag |
| Trp 746 | - | expression tag |
| Ser 747 | - | expression tag |
| His 748 | - | expression tag |
| Pro 749 | - | expression tag |
| Gln 750 | - | expression tag |
| Phe 751 | - | expression tag |
| Glu 752 | - | expression tag |
| Lys 753 | - | expression tag |
| Gly 754 | - | expression tag |
| Thr 755 | - | expression tag |
| Glu 756 | - | expression tag |
| Leu 757 | - | expression tag |
| Gly 758 | - | expression tag |
| Ser 759 | - | expression tag |
| Thr 760 | - | expression tag |
| Met 761 | - | expression tag |
| Ala 762 | - | expression tag |
| Ser 763 | - | expression tag |
| Tyr 764 | - | expression tag |
| Pro 765 | - | expression tag |
| Tyr 766 | - | expression tag |
| Asp 767 | - | expression tag |
| Val 768 | - | expression tag |
| Pro 769 | - | expression tag |
| Asp 770 | - | expression tag |
| Tyr 771 | - | expression tag |
| Ala 772 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 171015.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 7078.8 | |
| All* | Total formula weight | 178094.4 |
