9R1V

Structure of the human chimera HCN112 hyperpolarization-activated cyclic nucleotide-gated ion channel.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2	polymer	658	74099.0	4	UniProt (O60741) UniProt (Q9UL51) Pfam (PF08412) Pfam (PF00520) Pfam (PF00027)	Homo sapiens (human)	Brain cyclic nucleotide-gated channel 1,BCNG-1,Brain cyclic nucleotide-gated channel 2,BCNG-2

Sequence modifications

A, B, C, D: 1 - 401 (UniProt: O60741)
A, B, C, D: 402 - 636 (UniProt: Q9UL51)

PDB	External Database	Details
Ser 637	-	expression tag
Pro 638	-	expression tag
Gly 639	-	expression tag
Ala 640	-	expression tag
Ala 641	-	expression tag
Gly 642	-	expression tag
Gly 643	-	expression tag
Leu 644	-	expression tag
Asp 645	-	expression tag
Pro 646	-	expression tag
Gln 647	-	expression tag
Asp 648	-	expression tag
Ser 649	-	expression tag
Ala 650	-	expression tag
Arg 651	-	expression tag
Ser 652	-	expression tag
Arg 653	-	expression tag
Leu 654	-	expression tag
Ser 655	-	expression tag
Ser 656	-	expression tag
Asn 657	-	expression tag
Leu 658	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	296396.1
All*	Total formula weight	296396.1

*Water molecules are not included.