9R1F
Cryo-EM structure of human MATE1 in complex with metformin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Multidrug and toxin extrusion protein 1 | polymer | 570 | 61967.8 | 1 | UniProt (Q96FL8) | Homo sapiens (human) | MATE-1,hMATE-1,Solute carrier family 47 member 1 |
| 2 | B (H) | Heavy chain of Fab | polymer | 227 | 24250.0 | 1 | synthetic construct | ||
| 3 | C (L) | Light chain of Fab | polymer | 211 | 23140.7 | 1 | synthetic construct | ||
| 4 | D, E, F, G, H (A) | CHOLESTEROL | non-polymer | 386.7 | 5 | Chemie (CLR) | |||
| 5 | I (A) | Metformin | non-polymer | 129.2 | 1 | Chemie (MF8) | |||
| 6 | J, K, L (A, H, L) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 109358.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2062.4 | |
| All* | Total formula weight | 111420.9 |
