9R1C

Keap1 - inhibitor complex - 1

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Kelch-like ECH-associated protein 1	polymer	414	45854.3	1	UniProt (Q14145)	Homo sapiens (human)	Cytosolic inhibitor of Nrf2,INrf2,Kelch-like protein 19
2	B, C (A)	DIMETHYL SULFOXIDE	non-polymer		78.1	2	Chemie (DMS)
3	D (A)	2-[(4-methoxyphenyl)sulfonyl-[4-[(4-methoxyphenyl)sulfonyl-(1~{H}-1,2,3,4-tetrazol-5-ylmethyl)amino]naphthalen-1-yl]amino]ethanoic acid	non-polymer		638.7	1	Chemie (A1JB1)
4	E (A)	water	water		18.0	426	Chemie (HOH)

Sequence modifications

A: 321 - 609 (UniProt: Q14145)

PDB	External Database	Details
Met 196	-	initiating methionine
Ala 197	-	expression tag
Met 198	-	expression tag
Gly 199	-	expression tag
Ser 200	-	expression tag
Ser 201	-	expression tag
His 202	-	expression tag
His 203	-	expression tag
His 204	-	expression tag
His 205	-	expression tag
His 206	-	expression tag
His 207	-	expression tag
His 208	-	expression tag
His 209	-	expression tag
Ser 210	-	expression tag
Ser 211	-	expression tag
Gly 212	-	expression tag
Leu 213	-	expression tag
Val 214	-	expression tag
Pro 215	-	expression tag
Arg 216	-	expression tag
Gly 217	-	expression tag
Ser 218	-	expression tag
His 219	-	expression tag
Met 220	-	expression tag
Ala 221	-	expression tag
Ser 222	-	expression tag
Met 223	-	expression tag
Ser 224	-	expression tag
Asp 225	-	expression tag
Ser 226	-	expression tag
Glu 227	-	expression tag
Val 228	-	expression tag
Asn 229	-	expression tag
Gln 230	-	expression tag
Glu 231	-	expression tag
Ala 232	-	expression tag
Lys 233	-	expression tag
Pro 234	-	expression tag
Glu 235	-	expression tag
Val 236	-	expression tag
Lys 237	-	expression tag
Pro 238	-	expression tag
Glu 239	-	expression tag
Val 240	-	expression tag
Lys 241	-	expression tag
Pro 242	-	expression tag
Glu 243	-	expression tag
Thr 244	-	expression tag
His 245	-	expression tag
Ile 246	-	expression tag
Asn 247	-	expression tag
Leu 248	-	expression tag
Lys 249	-	expression tag
Val 250	-	expression tag
Ser 251	-	expression tag
Asp 252	-	expression tag
Gly 253	-	expression tag
Ser 254	-	expression tag
Ser 255	-	expression tag
Glu 256	-	expression tag
Ile 257	-	expression tag
Phe 258	-	expression tag
Phe 259	-	expression tag
Lys 260	-	expression tag
Ile 261	-	expression tag
Lys 262	-	expression tag
Lys 263	-	expression tag
Thr 264	-	expression tag
Thr 265	-	expression tag
Pro 266	-	expression tag
Leu 267	-	expression tag
Arg 268	-	expression tag
Arg 269	-	expression tag
Leu 270	-	expression tag
Met 271	-	expression tag
Glu 272	-	expression tag
Ala 273	-	expression tag
Phe 274	-	expression tag
Ala 275	-	expression tag
Lys 276	-	expression tag
Arg 277	-	expression tag
Gln 278	-	expression tag
Gly 279	-	expression tag
Lys 280	-	expression tag
Glu 281	-	expression tag
Met 282	-	expression tag
Asp 283	-	expression tag
Ser 284	-	expression tag
Leu 285	-	expression tag
Arg 286	-	expression tag
Phe 287	-	expression tag
Leu 288	-	expression tag
Tyr 289	-	expression tag
Asp 290	-	expression tag
Gly 291	-	expression tag
Ile 292	-	expression tag
Arg 293	-	expression tag
Ile 294	-	expression tag
Gln 295	-	expression tag
Ala 296	-	expression tag
Asp 297	-	expression tag
Gln 298	-	expression tag
Thr 299	-	expression tag
Pro 300	-	expression tag
Glu 301	-	expression tag
Asp 302	-	expression tag
Leu 303	-	expression tag
Asp 304	-	expression tag
Met 305	-	expression tag
Glu 306	-	expression tag
Asp 307	-	expression tag
Asn 308	-	expression tag
Asp 309	-	expression tag
Ile 310	-	expression tag
Ile 311	-	expression tag
Glu 312	-	expression tag
Ala 313	-	expression tag
His 314	-	expression tag
Arg 315	-	expression tag
Glu 316	-	expression tag
Gln 317	-	expression tag
Ile 318	-	expression tag
Gly 319	-	expression tag
Gly 320	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	45854.3
Non-Polymers*	Number of molecules	3
	Total formula weight	794.9
All*	Total formula weight	46649.2

*Water molecules are not included.