9R01
Complex I from Ovis aries in presence of D1 inhibitor, Closed state
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NADH-ubiquinone oxidoreductase chain 3 | polymer | 115 | 13106.5 | 1 | UniProt (O78753) Pfam (PF00507) | Ovis aries (sheep) | NADH dehydrogenase subunit 3 |
| 2 | B (H) | NADH-ubiquinone oxidoreductase chain 1 | polymer | 318 | 35884.9 | 1 | UniProt (O78747) Pfam (PF00146) | Ovis aries (sheep) | NADH dehydrogenase subunit 1 |
| 3 | C (J) | NADH-ubiquinone oxidoreductase chain 6 | polymer | 175 | 19126.6 | 1 | UniProt (O78757) Pfam (PF00499) | Ovis aries (sheep) | NADH dehydrogenase subunit 6 |
| 4 | D (K) | NADH-ubiquinone oxidoreductase chain 4L | polymer | 98 | 10868.2 | 1 | UniProt (O78754) Pfam (PF00420) | Ovis aries (sheep) | NADH dehydrogenase subunit 4L |
| 5 | E (L) | NADH-ubiquinone oxidoreductase chain 5 | polymer | 606 | 68438.9 | 1 | UniProt (O78756) Pfam (PF00662) Pfam (PF00361) Pfam (PF06455) | Ovis aries (sheep) | NADH dehydrogenase subunit 5 |
| 6 | F (M) | NADH-ubiquinone oxidoreductase chain 4 | polymer | 459 | 52086.7 | 1 | UniProt (O78755) Pfam (PF01059) Pfam (PF00361) | Ovis aries (sheep) | NADH dehydrogenase subunit 4 |
| 7 | G (N) | NADH-ubiquinone oxidoreductase chain 2 | polymer | 347 | 39149.8 | 1 | UniProt (O78748) Pfam (PF00361) Pfam (PF06444) | Ovis aries (sheep) | NADH dehydrogenase subunit 2 |
| 8 | H (V) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 | polymer | 141 | 14636.8 | 1 | UniProt (A0A8V6VBD6) | Ovis aries (sheep) | Complex I-B14.7,NADH-ubiquinone oxidoreductase subunit B14.7 |
| 9 | I (W) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial | polymer | 189 | 21614.2 | 1 | UniProt (A0A8V6WJW2) | Ovis aries (sheep) | Complex I-SGDH,NADH-ubiquinone oxidoreductase SGDH subunit |
| 10 | J, SA (X, j) | Acyl carrier protein | polymer | 87 | 10032.5 | 2 | UniProt (W5NQT7) | Ovis aries (sheep) | |
| 11 | K (Y) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | polymer | 171 | 20008.0 | 1 | UniProt (A0A8V6W0E9) | Ovis aries (sheep) | |
| 12 | L (Z) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | polymer | 175 | 20880.8 | 1 | UniProt (A0A7M4DUF5) | Ovis aries (sheep) | Complex I-PDSW,NADH-ubiquinone oxidoreductase PDSW subunit |
| 13 | M (k) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | polymer | 355 | 40557.1 | 1 | UniProt (A0A8V6WD49) | Ovis aries (sheep) | |
| 14 | N (l) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | polymer | 106 | 12605.6 | 1 | UniProt (A0A836D7R1) | Ovis aries (sheep) | Complex I-15 kDa,NADH-ubiquinone oxidoreductase 15 kDa subunit |
| 15 | O (m) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 | polymer | 84 | 9325.9 | 1 | UniProt (A0A8V6UZQ8) | Ovis aries (sheep) | Complex I-B9,NADH-ubiquinone oxidoreductase B9 subunit |
| 16 | P (n) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 | polymer | 98 | 11146.7 | 1 | UniProt (A0A6P7DQB1) | Ovis aries (sheep) | Complex I-B12,NADH-ubiquinone oxidoreductase B12 subunit |
| 17 | Q (o) | NADH dehydrogenase [ubiquinone] 1 subunit C2 | polymer | 122 | 14431.7 | 1 | UniProt (W5P9Q8) | Ovis aries (sheep) | |
| 18 | R (p) | NADH:ubiquinone oxidoreductase subunit B4 | polymer | 130 | 15236.4 | 1 | UniProt (W5QF73) | Ovis aries (sheep) | |
| 19 | S (q) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | polymer | 144 | 16766.5 | 1 | UniProt (A0A6P3E975) | Ovis aries (sheep) | |
| 20 | T (r) | Mitochondrial complex I, B17 subunit | polymer | 128 | 15565.1 | 1 | UniProt (W5PZE3) | Ovis aries (sheep) | |
| 21 | U (s) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 | polymer | 137 | 16413.8 | 1 | UniProt (A0A8V6V740) | Ovis aries (sheep) | Complex I-B18,NADH-ubiquinone oxidoreductase B18 subunit |
| 22 | V (t) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | polymer | 179 | 21779.9 | 1 | UniProt (A0A8V6VHV8) | Ovis aries (sheep) | Complex I-B22,NADH-ubiquinone oxidoreductase B22 subunit |
| 23 | W (u) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial | polymer | 108 | 12226.8 | 1 | UniProt (A0A8N7XJB4) | Ovis aries (sheep) | Complex I-AGGG,NADH-ubiquinone oxidoreductase AGGG subunit |
| 24 | X (v) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | polymer | 186 | 21752.6 | 1 | UniProt (W5Q1B0) | Ovis aries (sheep) | Complex I-ASHI,NADH-ubiquinone oxidoreductase ASHI subunit |
| 25 | Y (w) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | polymer | 154 | 17410.7 | 1 | UniProt (A0A8V6VZU3) | Ovis aries (sheep) | Complex I-ESSS,NADH-ubiquinone oxidoreductase ESSS subunit |
| 26 | Z (x) | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial | polymer | 76 | 8802.2 | 1 | UniProt (A0A6P3EDV0) | Ovis aries (sheep) | Complex I-KFYI,NADH-ubiquinone oxidoreductase KFYI subunit |
| 27 | AA (y) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | polymer | 58 | 7075.3 | 1 | UniProt (A0A7M4DUG1) | Ovis aries (sheep) | Complex I-MNLL,NADH-ubiquinone oxidoreductase MNLL subunit |
| 28 | BA (z) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | polymer | 70 | 8211.5 | 1 | UniProt (A0A6P9FRJ5) | Ovis aries (sheep) | Complex I-MWFE,NADH-ubiquinone oxidoreductase MWFE subunit |
| 29 | CA (1) | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | polymer | 464 | 50687.8 | 1 | UniProt (W5PUX0) | Ovis aries (sheep) | |
| 30 | DA (2) | Mitochondrial complex I, 24 kDa subunit | polymer | 246 | 27373.6 | 1 | UniProt (W5NRY1) | Ovis aries (sheep) | |
| 31 | EA (3) | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | polymer | 727 | 79519.3 | 1 | UniProt (A0A8V6WEB9) Pfam (PF13510) Pfam (PF10588) Pfam (PF22117) Pfam (PF22151) Pfam (PF00384) Pfam (PF09326) | Ovis aries (sheep) | |
| 32 | FA (4) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | polymer | 463 | 52661.5 | 1 | UniProt (A0A6P3DZ89) | Ovis aries (sheep) | Complex I-49kD,NADH-ubiquinone oxidoreductase 49 kDa subunit |
| 33 | GA (5) | NADH:ubiquinone oxidoreductase core subunit S3 | polymer | 266 | 30384.6 | 1 | UniProt (W5PB27) | Ovis aries (sheep) | |
| 34 | HA (6) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial | polymer | 223 | 24622.9 | 1 | UniProt (A0A6P7E5N1) | Ovis aries (sheep) | Complex I-20kD,NADH-ubiquinone oxidoreductase 20 kDa subunit |
| 35 | IA (9) | Complex I-23kD | polymer | 217 | 24496.1 | 1 | UniProt (A0A6P3TFB2) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8,mitochondrial,NADH-ubiquinone oxidoreductase 23 kDa subunit |
| 36 | JA (a) | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial | polymer | 109 | 11916.5 | 1 | UniProt (A0A6P3E7B5) | Ovis aries (sheep) | Complex I-9kD,NADH-ubiquinone oxidoreductase 9 kDa subunit |
| 37 | KA (b) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | polymer | 124 | 13457.2 | 1 | UniProt (A0A6P7EX23) | Ovis aries (sheep) | |
| 38 | LA (c) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | polymer | 170 | 19382.0 | 1 | UniProt (W5PE07) | Ovis aries (sheep) | Complex I-18 kDa,NADH-ubiquinone oxidoreductase 18 kDa subunit |
| 39 | MA (d) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial | polymer | 380 | 43025.6 | 1 | UniProt (A0A8V6VJX1) | Ovis aries (sheep) | Complex I-39kD,NADH-ubiquinone oxidoreductase 39 kDa subunit |
| 40 | NA (e) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | polymer | 99 | 11097.8 | 1 | UniProt (A0A8V6WE19) | Ovis aries (sheep) | |
| 41 | OA (f) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | polymer | 116 | 13287.5 | 1 | UniProt (A0A8V6VT05) | Ovis aries (sheep) | Complex I subunit B13,Complex I-13kD-B,NADH-ubiquinone oxidoreductase 13 kDa-B subunit |
| 42 | PA (g) | NADH:ubiquinone oxidoreductase subunit A6 | polymer | 140 | 16302.8 | 1 | UniProt (W5QC06) | Ovis aries (sheep) | |
| 43 | QA (h) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | polymer | 113 | 12425.2 | 1 | UniProt (A0A6P3E9B7) | Ovis aries (sheep) | Complex I-B14.5a,NADH-ubiquinone oxidoreductase subunit B14.5a |
| 44 | RA (i) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | polymer | 145 | 17115.5 | 1 | UniProt (A0A8N7XJ18) | Ovis aries (sheep) | |
| 45 | CB, CC, DB, EB, HB... (N, i, V, o, 4...) | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 13 | Chemie (3PE) | |||
| 46 | AB, BB, VB, XB, YA (M, 6, 9, L) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 5 | Chemie (PC1) | |||
| 47 | FB (k) | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (DGT) | |||
| 48 | GB (k) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 49 | IB (s) | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) PubChem (11005) | |||
| 50 | DC, JB (j, t) | S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate | non-polymer | 568.7 | 2 | Chemie (ZMP) PubChem (24941266) | |||
| 51 | KB, OB, PB, UB, YB... (1, 3, 6, 9) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 6 | Chemie (SF4) | |||
| 52 | LB (1) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) PubChem (643976) | |||
| 53 | MB (1) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 1 | Chemie (NAI) | |||
| 54 | NB, QB (2, 3) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 55 | RB (3) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) PubChem (813) | |||
| 56 | TB (4) | (7~{S})-7-[(2~{S})-1-(6-azanylpurin-3-yl)propan-2-yl]-3-methyl-6,7,8,9-tetrahydro-5~{a}~{H}-pyrano[4,3-b]chromen-1-one | non-polymer | 393.4 | 1 | Chemie (A1JBT) | |||
| 57 | AC (b) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) PubChem (32051) | |||
| 58 | BC (d) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) |
Sequence modifications
V: 1 - 140 (UniProt: A0A8V6VBD6)
h: 1 - 112 (UniProt: A0A6P3E9B7)
| PDB | External Database | Details |
|---|---|---|
| Ace 1 | - | acetylation |
| PDB | External Database | Details |
|---|---|---|
| Ace 1 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 45 |
| Total formula weight | 1032929.9 | |
| Non-Polymers* | Number of molecules | 37 |
| Total formula weight | 20399.5 | |
| All* | Total formula weight | 1053329.4 |
