9QZQ
CryoEM structure of nanodisc-reconstituted human NTCP in complex with grafted NTCP_Nb1 and NabFab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium/bile acid cotransporter | polymer | 349 | 38149.9 | 1 | UniProt (Q14973) Pfam (PF01758) | Homo sapiens (human) | Cell growth-inhibiting gene 29 protein,Na(+)/bile acid cotransporter,Na(+)/taurocholate transport protein,Sodium/taurocholate cotransporting polypeptide,Solute carrier family 10 member 1 |
| 2 | B (H) | NabFab - Heavy Chain | polymer | 239 | 25684.5 | 1 | Homo sapiens | ||
| 3 | C (L) | NabFab - Light Chain | polymer | 215 | 23258.8 | 1 | Homo sapiens | ||
| 4 | D (N) | Grafted Nanobody NTCP_Nb1 | polymer | 137 | 15233.8 | 1 | Vicugna pacos | ||
| 5 | E, F (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 102327.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 46.0 | |
| All* | Total formula weight | 102372.9 |
