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9QYI

Crystal structure of human S-adenosyl-L-homocysteine hydrolase complex with adenosine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, D, E, F...)
Adenosylhomocysteinasepolymer43147640.88UniProt (P23526)
Pfam (PF05221)
Pfam (PF00670)
Homo sapiens (human)AdoHcyase,S-adenosyl-L-homocysteine hydrolase
2AA, FA, I, IA, M...
(G, C, A, H, B...)
NICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.48Chemie (NAD)
3BA, GA, J, JA, N...
(G, C, A, H, B...)
ADENOSINEnon-polymer267.28Chemie (ADN)
PubChem (60961)
4CA, DA, HA, K, LA...
(G, C, A, H, B...)
POTASSIUM IONnon-polymer39.19Chemie (K)
PubChem (813)
5EA, L, S, Z
(G, A, D, F)
SULFATE IONnon-polymer96.14Chemie (SO4)
6KA
(H)
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.21Chemie (MPD)
PubChem (5288834)
7MA, NA, OA, PA, QA...
(A, B, D, E, F...)
waterwater18.02713Chemie (HOH)
Sequence modifications
A, B, D, E, F, G, C, H: 2 - 432 (UniProt: P23526)
PDBExternal DatabaseDetails
Asn 86Asp 86variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight381126.2
Non-Polymers*Number of molecules30
Total formula weight8299.6
All*Total formula weight389425.9
*Water molecules are not included.

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PDB entries from 2026-07-08

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