9QWP

Structure of the human RalGAP2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Ral GTPase-activating protein subunit alpha-2	polymer	1899	214046.5	2	UniProt (Q2PPJ7) Pfam (PF20412) Pfam (PF02145)	Homo sapiens (human)	250 kDa substrate of Akt,AS250,p220
2	B, C (B, C)	Ral GTPase-activating protein subunit beta	polymer	1528	170796.4	2	UniProt (Q86X10) Pfam (PF20412)	Homo sapiens (human)	p170

Sequence modifications

A, D: 2 - 1873 (UniProt: Q2PPJ7)

PDB	External Database	Details
Met -25	-	initiating methionine
Asp -24	-	expression tag
Tyr -23	-	expression tag
Lys -22	-	expression tag
Asp -21	-	expression tag
His -20	-	expression tag
Asp -19	-	expression tag
Gly -18	-	expression tag
Asp -17	-	expression tag
Tyr -16	-	expression tag
Lys -15	-	expression tag
Asp -14	-	expression tag
His -13	-	expression tag
Asp -12	-	expression tag
Ile -11	-	expression tag
Asp -10	-	expression tag
Tyr -9	-	expression tag
Lys -8	-	expression tag
Asp -7	-	expression tag
Asp -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Lys -3	-	expression tag
Leu -2	-	expression tag
Ala -1	-	expression tag
Ala 0	-	expression tag
Ala 1	-	expression tag

B, C: 1 - 1494 (UniProt: Q86X10)

PDB	External Database	Details
Met -33	-	initiating methionine
Tyr -32	-	expression tag
Pro -31	-	expression tag
Tyr -30	-	expression tag
Asp -29	-	expression tag
Val -28	-	expression tag
Pro -27	-	expression tag
Asp -26	-	expression tag
Tyr -25	-	expression tag
Ala -24	-	expression tag
Gly -23	-	expression tag
Ser -22	-	expression tag
Tyr -21	-	expression tag
Pro -20	-	expression tag
Tyr -19	-	expression tag
Asp -18	-	expression tag
Val -17	-	expression tag
Pro -16	-	expression tag
Asp -15	-	expression tag
Tyr -14	-	expression tag
Ala -13	-	expression tag
Gly -12	-	expression tag
Ser -11	-	expression tag
Tyr -10	-	expression tag
Pro -9	-	expression tag
Tyr -8	-	expression tag
Asp -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Asp -4	-	expression tag
Tyr -3	-	expression tag
Ala -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	769685.8
All*	Total formula weight	769685.8

*Water molecules are not included.