9QWM
Crystal structure of catalytic domain of Rv1625c bound to inhibitory Darpin G11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Adenylate cyclase | polymer | 254 | 28202.8 | 1 | UniProt (P9WQ35) Pfam (PF00211) | Mycobacterium tuberculosis | ATP pyrophosphate-lyase,Adenylyl cyclase |
| 2 | B (B) | Darpin G11 | polymer | 182 | 20055.4 | 1 | synthetic construct | ||
| 3 | C (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A: 6 - 233 (UniProt: P9WQ35)
| PDB | External Database | Details |
|---|---|---|
| Met -20 | - | initiating methionine |
| Gly -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Ser -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Glu -4 | - | expression tag |
| Val -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Phe -1 | - | expression tag |
| Gln 0 | - | expression tag |
| Gly 1 | - | expression tag |
| Pro 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Gly 4 | - | expression tag |
| His 5 | - | expression tag |
| Met 6 | Leu 202 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48258.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 48350.3 |
