9QTU

human PAN2-PAN3 deadenylase complex in the apo state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Isoform 3 of PAN2-PAN3 deadenylation complex subunit PAN3	polymer	863	92526.5	2	UniProt (Q58A45) Pfam (PF18101)	Homo sapiens (human)	PAB1P-dependent poly(A)-specific ribonuclease,Poly(A)-nuclease deadenylation complex subunit 3,PAN deadenylation complex subunit 3
2	C (C)	PAN2-PAN3 deadenylation complex catalytic subunit PAN2	polymer	1202	135523.1	1	UniProt (Q504Q3) Pfam (PF20770) Pfam (PF13423) Pfam (PF00929)	Homo sapiens (human)	Inactive ubiquitin carboxyl-terminal hydrolase 52,PAB1P-dependent poly(A)-specific ribonuclease,Poly(A)-nuclease deadenylation complex subunit 2,PAN deadenylation complex subunit 2

Sequence modifications

A, B: 1 - 833 (UniProt: Q58A45)

PDB	External Database	Details
Ser 834	-	expression tag
Ala 835	-	expression tag
Trp 836	-	expression tag
Ser 837	-	expression tag
His 838	-	expression tag
Pro 839	-	expression tag
Gln 840	-	expression tag
Phe 841	-	expression tag
Glu 842	-	expression tag
Lys 843	-	expression tag
Gly 844	-	expression tag
Gly 845	-	expression tag
Gly 846	-	expression tag
Ser 847	-	expression tag
Gly 848	-	expression tag
Gly 849	-	expression tag
Gly 850	-	expression tag
Ser 851	-	expression tag
Gly 852	-	expression tag
Gly 853	-	expression tag
Ser 854	-	expression tag
Ala 855	-	expression tag
Trp 856	-	expression tag
Ser 857	-	expression tag
His 858	-	expression tag
Pro 859	-	expression tag
Gln 860	-	expression tag
Phe 861	-	expression tag
Glu 862	-	expression tag
Lys 863	-	expression tag

C: 1 - 1202 (UniProt: Q504Q3)

PDB	External Database	Details
Leu 179	Ile 179	variant

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	320576.2
All*	Total formula weight	320576.2

*Water molecules are not included.