9QRH

Protein Kinase CK2 and bivalent inhibitors

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Casein kinase II subunit alpha	polymer	359	42799.6	2	UniProt (P68400) Pfam (PF00069)	Homo sapiens (human)	CK II alpha
2	C, J (A, B)	5-[[(3~{E})-3-[4-[2-(3,4-dichlorophenyl)ethylamino]-4-oxidanylidene-butanoyl]iminopropyl]amino]benzo[c][2,6]naphthyridine-8-carboxylic acid	non-polymer		566.4	2	Chemie (A1I9M)
3	D, E, F, G, H... (A, B)	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
4	N, O (A, B)	water	water		18.0	20	Chemie (HOH)

Sequence modifications

A, B: 1 - 337 (UniProt: P68400)

PDB	External Database	Details
Met -21	-	initiating methionine
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Leu -9	-	expression tag
Gly -8	-	expression tag
Thr -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	85599.3
Non-Polymers*	Number of molecules	11
	Total formula weight	1997.4
All*	Total formula weight	87596.7

*Water molecules are not included.