9QR8
Gliadin degrading prolyl endopeptidase Celiacase (neprosin C334V)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein neprosin | polymer | 367 | 40547.8 | 1 | UniProt (C0HLV2) | Nepenthes alata x Nepenthes ventricosa | Npr1,Prolyl endopeptidase |
| 2 | B (B) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 3 | C (C) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E, F (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) PubChem (312) | |||
| 6 | G (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) PubChem (3777159) | |||
| 7 | H (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 8 | I (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 9 | J, K, L, M, N (A) | GLYCINE | non-polymer | 75.1 | 5 | Chemie (GLY) PubChem (750) | |||
| 10 | O (A) | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A: 25 - 380 (UniProt: C0HLV2)
| PDB | External Database | Details |
|---|---|---|
| Met 23 | - | initiating methionine |
| Val 24 | - | expression tag |
| Val 334 | Cys 334 | engineered mutation |
| Ala 401 | - | expression tag |
| Ile 402 | - | expression tag |
| Ala 403 | - | expression tag |
| His 404 | - | expression tag |
| His 405 | - | expression tag |
| His 406 | - | expression tag |
| His 407 | - | expression tag |
| His 408 | - | expression tag |
| His 409 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40547.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 953.9 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 862.7 | |
| All* | Total formula weight | 42364.4 |
