Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9QQA

Ternary complex of translating ribosome, NAC and NMT1

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A2)	18S rRNA	polymer	1870	603928.3	1		Oryctolagus cuniculus (rabbit)
2	B (AA)	Small ribosomal subunit protein eS27	polymer	84	9480.2	1	UniProt (G1TZ76) Pfam (PF01667)	Oryctolagus cuniculus (rabbit)
3	C (AB)	Small ribosomal subunit protein eS28	polymer	69	7855.1	1	UniProt (G1TIB4) Pfam (PF01200)	Oryctolagus cuniculus (rabbit)
4	D (AC)	Ubiquitin-ribosomal protein eS31 fusion protein	polymer	156	18004.0	1	UniProt (G1SK22) Pfam (PF00240) Pfam (PF01599)	Oryctolagus cuniculus (rabbit)
5	E (AD)	Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein	polymer	133	14498.9	1	UniProt (G1T8A2) Pfam (PF00240) Pfam (PF04758)	Oryctolagus cuniculus (rabbit)
6	F (AE)	eS26	polymer	115	13047.5	1	UniProt (A0A2K5LQY6) Pfam (PF01283)	Oryctolagus cuniculus (rabbit)
7	G (AF)	Small ribosomal subunit protein RACK1	polymer	317	35115.7	1	UniProt (G1SJB4) Pfam (PF00400)	Oryctolagus cuniculus (rabbit)	RACK1
8	H (AG)	Small ribosomal subunit protein uS14	polymer	56	6690.8	1	UniProt (G1U7M4) Pfam (PF00253)	Oryctolagus cuniculus (rabbit)	uS14
9	I (AT)	P site Phe tRNA	polymer	76	24451.6	1	GenBank (2082008580)	Oryctolagus cuniculus (rabbit)
10	J (AZ)	Small ribosomal subunit protein uS2	polymer	295	32822.8	1	UniProt (G1TLT8) Pfam (PF00318) Pfam (PF16122)	Oryctolagus cuniculus (rabbit)	37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40
11	K (Aa)	40S ribosomal protein S3a	polymer	264	30002.1	1	UniProt (G1SS70) Pfam (PF01015)	Oryctolagus cuniculus (rabbit)	RPS3A
12	L (Ab)	40S ribosomal protein S2	polymer	293	31285.4	1	UniProt (O18789) Pfam (PF00333) Pfam (PF03719)	Oryctolagus cuniculus (rabbit)
13	M (Ac)	40S ribosomal protein S3	polymer	281	31146.6	1	UniProt (G1TNM3) Pfam (PF07650) Pfam (PF00189)	Oryctolagus cuniculus (rabbit)	uS3
14	N (Ad)	40S ribosomal protein S4	polymer	263	29654.9	1	UniProt (G1TK17) Pfam (PF08071) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121)	Oryctolagus cuniculus (rabbit)
15	O (Ae)	Small ribosomal subunit protein uS7	polymer	204	22913.5	1	UniProt (G1TFM5) Pfam (PF00177)	Oryctolagus cuniculus (rabbit)
16	P (Af)	40S ribosomal protein S6	polymer	249	28751.9	1	UniProt (G1TM55) Pfam (PF01092)	Oryctolagus cuniculus (rabbit)
17	Q (Ag)	40S ribosomal protein S7	polymer	432	47356.2	1	UniProt (G1SVB0)	Oryctolagus cuniculus (rabbit)
18	R (Ah)	40S ribosomal protein S8	polymer	208	24263.4	1	UniProt (G1TJW1) Pfam (PF01201)	Oryctolagus cuniculus (rabbit)
19	S (Ai)	Small ribosomal subunit protein uS4	polymer	194	22641.6	1	UniProt (B7NZS8) Pfam (PF00163) Pfam (PF01479)	Oryctolagus cuniculus (rabbit)
20	T (Aj)	S10_plectin domain-containing protein	polymer	165	18933.8	1	UniProt (G1TPV3) Pfam (PF03501)	Oryctolagus cuniculus (rabbit)	eS10
21	U (Ak)	Small ribosomal subunit protein uS17	polymer	158	18468.8	1	UniProt (G1TRM4) Pfam (PF16205) Pfam (PF00366)	Oryctolagus cuniculus (rabbit)
22	V (Al)	Small ribosomal subunit protein eS12	polymer	132	14539.0	1	UniProt (G1SFR8) Pfam (PF01248)	Oryctolagus cuniculus (rabbit)
23	W (Am)	Small ribosomal subunit protein uS15	polymer	151	17259.4	1	UniProt (G1SP51) Pfam (PF08069) Pfam (PF00312)	Oryctolagus cuniculus (rabbit)	uS15
24	X (An)	Small ribosomal subunit protein uS11	polymer	151	16302.8	1	UniProt (G1T1F0) Pfam (PF00411)	Oryctolagus cuniculus (rabbit)
25	Y (Ao)	Small ribosomal subunit protein uS19	polymer	145	17049.2	1	UniProt (G1U0Q2) Pfam (PF00203)	Oryctolagus cuniculus (rabbit)
26	Z (Ap)	Small ribosomal subunit protein uS9	polymer	172	19213.5	1	UniProt (G1SGX4) Pfam (PF00380)	Oryctolagus cuniculus (rabbit)	uS9
27	AA (Aq)	Small ribosomal subunit protein eS17	polymer	135	15552.1	1	UniProt (G1TU13) Pfam (PF00833)	Oryctolagus cuniculus (rabbit)
28	BA (Ar)	Small ribosomal subunit protein uS13	polymer	152	17654.6	1	UniProt (G1TPG3) Pfam (PF00416)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S18
29	CA (As)	40S ribosomal protein S19	polymer	145	16104.6	1	UniProt (G1TN62) Pfam (PF01090)	Oryctolagus cuniculus (rabbit)
30	DA (At)	Small ribosomal subunit protein uS10	polymer	119	13398.8	1	UniProt (G1SIZ2) Pfam (PF00338)	Oryctolagus cuniculus (rabbit)
31	EA (Au)	Small ribosomal subunit protein eS21	polymer	84	9165.4	1	UniProt (G1TM82) Pfam (PF01249)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S21
32	FA (Av)	Small ribosomal subunit protein uS8	polymer	130	14865.6	1	UniProt (G1TG89) Pfam (PF00410)	Oryctolagus cuniculus (rabbit)
33	GA (Aw)	40S ribosomal protein S23	polymer	143	15860.7	1	UniProt (G1SZ47) Pfam (PF00164)	Oryctolagus cuniculus (rabbit)
34	HA (Ax)	40S ribosomal protein S24	polymer	130	15107.9	1	UniProt (G1T3D8) Pfam (PF01282)	Oryctolagus cuniculus (rabbit)
35	IA (Ay)	Small ribosomal subunit protein eS25	polymer	124	13645.0	1	UniProt (G1TDB3) Pfam (PF03297)	Oryctolagus cuniculus (rabbit)
36	JA (Az)	Small ribosomal subunit protein eS32	polymer	25	3473.5	1	UniProt (A0A087WNH4) Pfam (PF05162)	Oryctolagus cuniculus (rabbit)
37	KA (B5)	28S rRNA	polymer	4808	1557519.5	1	GenBank (GBCN01009604.1)	Oryctolagus cuniculus (rabbit)
38	LA (B7)	5S rRNA	polymer	120	38691.9	1	GenBank (4CXE_4)	Oryctolagus cuniculus (rabbit)
39	MA (B8)	5.8S rRNA	polymer	158	50809.0	1	GenBank (GBCN01009604.1)	Oryctolagus cuniculus (rabbit)
40	NA (BA)	Large ribosomal subunit protein uL2	polymer	257	28103.9	1	UniProt (G1TT27) Pfam (PF00181) Pfam (PF03947)	Oryctolagus cuniculus (rabbit)	60S ribosomal protein L8
41	OA (BB)	Ribosomal protein L3	polymer	403	46121.0	1	UniProt (G1TL06) Pfam (PF00297)	Oryctolagus cuniculus (rabbit)
42	PA (BC)	Large ribosomal subunit protein uL4	polymer	413	46283.7	1	UniProt (G1SVW5) Pfam (PF00573) Pfam (PF14374)	Oryctolagus cuniculus (rabbit)	60S ribosomal protein L4
43	QA (BE)	60S ribosomal protein L6	polymer	291	33028.3	1	UniProt (G1SKF7) Pfam (PF03868) Pfam (PF01159)	Oryctolagus cuniculus (rabbit)
44	RA (BF)	Ribosomal Protein uL30	polymer	247	29201.8	1	UniProt (G1TUB1) Pfam (PF08079) Pfam (PF00327)	Oryctolagus cuniculus (rabbit)
45	SA (BG)	60S ribosomal protein L7a	polymer	266	30061.8	1	UniProt (P62424) Pfam (PF01248)	Oryctolagus cuniculus (rabbit)	Large ribosomal subunit protein eL8,PLA-X polypeptide,Surfeit locus protein 3
46	TA (BH)	60S ribosomal protein L9	polymer	192	21871.4	1	UniProt (G1SWI6) Pfam (PF00347)	Oryctolagus cuniculus (rabbit)
47	UA (BI)	60S ribosomal protein L10	polymer	214	24643.1	1	UniProt (B7NZQ2) Pfam (PF00252)	Oryctolagus cuniculus (rabbit)	Ribosomal protein L10
48	VA (BJ)	60S ribosomal protein L11	polymer	178	20288.5	1	UniProt (G1TUB8) Pfam (PF00281) Pfam (PF00673)	Oryctolagus cuniculus (rabbit)
49	WA (BK)	Nascent chain	polymer	12	1039.3	1		Oryctolagus cuniculus
50	XA (BL)	Large ribosomal subunit protein eL13	polymer	211	24331.7	1	UniProt (G1TKB3) Pfam (PF01294)	Oryctolagus cuniculus (rabbit)	60S ribosomal protein L13
51	YA (BM)	60S ribosomal protein L14	polymer	218	23870.5	1	UniProt (G1SZ12) Pfam (PF01929)	Oryctolagus cuniculus (rabbit)
52	ZA (BN)	Ribosomal protein L15	polymer	204	24207.3	1	UniProt (G1T0C1) Pfam (PF00827)	Oryctolagus cuniculus (rabbit)
53	AB (BO)	Large ribosomal subunit protein uL13	polymer	203	23533.3	1	UniProt (G1TVS8)	Oryctolagus cuniculus (rabbit)	60S ribosomal protein L13a
54	BB (BP)	Large ribosomal subunit protein uL22	polymer	184	21444.2	1	UniProt (G1SCJ6) Pfam (PF00237)	Oryctolagus cuniculus (rabbit)	60S ribosomal protein L17
55	CB (BQ)	eL18	polymer	188	21699.7	1	UniProt (F6QKI9) Pfam (PF17135)	Oryctolagus cuniculus (rabbit)
56	DB (BR)	Ribosomal protein L19	polymer	196	23535.3	1	UniProt (G1TJR3) Pfam (PF01280)	Oryctolagus cuniculus (rabbit)
57	EB (BS)	Large ribosomal subunit protein eL20	polymer	176	20749.4	1	UniProt (G1TTY7) Pfam (PF01775)	Oryctolagus cuniculus (rabbit)	60S ribosomal protein L18a
58	FB (BT)	60S ribosomal protein L21	polymer	160	18610.0	1	UniProt (G1SHQ2) Pfam (PF01157)	Oryctolagus cuniculus (rabbit)	eL21
59	GB (BU)	60S ribosomal protein L22	polymer	128	14756.9	1	UniProt (G1TSG1) Pfam (PF01776)	Oryctolagus cuniculus (rabbit)
60	HB (BV)	Ribosomal protein L23	polymer	140	14892.5	1	UniProt (G1T6D1) Pfam (PF00238)	Oryctolagus cuniculus (rabbit)
61	IB (BW)	Ribosomal protein L24	polymer	157	17825.1	1	UniProt (G1SE28) Pfam (PF01246)	Oryctolagus cuniculus (rabbit)	eL24
62	JB (BX)	Large ribosomal subunit protein uL23	polymer	156	17768.2	1	UniProt (G1SE76) Pfam (PF03939) Pfam (PF00276)	Oryctolagus cuniculus (rabbit)	uL23
63	KB (BY)	Ribosomal protein L26	polymer	145	17303.4	1	UniProt (G1SQH0) Pfam (PF16906) Pfam (PF00467)	Oryctolagus cuniculus (rabbit)
64	LB (BZ)	60S ribosomal protein L27	polymer	136	15835.8	1	UniProt (G1TXF6) Pfam (PF00467) Pfam (PF01777)	Oryctolagus cuniculus (rabbit)
65	MB (Ba)	60S ribosomal protein L27a	polymer	148	16635.6	1	UniProt (G1SNY0) Pfam (PF00828)	Oryctolagus cuniculus (rabbit)
66	NB (Bb)	60S ribosomal protein L29	polymer	245	26721.7	1	UniProt (G1SGR6) Pfam (PF01779)	Oryctolagus cuniculus (rabbit)
67	OB (Bc)	60S ribosomal protein L30	polymer	115	12807.1	1	UniProt (G1TDL2) Pfam (PF01248)	Oryctolagus cuniculus (rabbit)	eL30
68	PB (Bd)	60S ribosomal protein L31	polymer	125	14494.9	1	UniProt (G1SHG0) Pfam (PF01198)	Oryctolagus cuniculus (rabbit)	eL31
69	QB (Be)	Ribosomal protein L32	polymer	135	15898.9	1	UniProt (A0AAA9WVN6)	Oryctolagus cuniculus (rabbit)
70	RB (Bf)	60S ribosomal protein L35a	polymer	110	12580.8	1	UniProt (G1SF08) Pfam (PF01247)	Oryctolagus cuniculus (rabbit)	eL33
71	SB (Bg)	60S ribosomal protein L34	polymer	117	13326.1	1	UniProt (G1TXG5) Pfam (PF01199)	Oryctolagus cuniculus (rabbit)
72	TB (Bh)	60S ribosomal protein L35	polymer	123	14566.6	1	UniProt (G1SIT5) Pfam (PF00831)	Oryctolagus cuniculus (rabbit)	uL29
73	UB (Bi)	60S ribosomal protein L36	polymer	105	12263.8	1	UniProt (G1TTQ5) Pfam (PF01158)	Oryctolagus cuniculus (rabbit)
74	VB (Bj)	Ribosomal protein L37	polymer	97	11111.0	1	UniProt (U3KPD5) Pfam (PF01907)	Oryctolagus cuniculus (rabbit)
75	WB (Bk)	60S ribosomal protein L38	polymer	70	8238.9	1	UniProt (G1U001) Pfam (PF01781)	Oryctolagus cuniculus (rabbit)	eL38
76	XB (Bl)	60S ribosomal protein L39-like	polymer	51	6455.8	1	UniProt (G1TTN1) Pfam (PF00832)	Oryctolagus cuniculus (rabbit)	eL39
77	YB (Bm)	Ubiquitin-ribosomal protein eL40 fusion protein	polymer	128	14800.5	1	UniProt (P0DXC2)	Oryctolagus cuniculus (rabbit)	Ubiquitin A-52 residue ribosomal protein fusion product 1
78	ZB (Bo)	Large ribosomal subunit protein eL42	polymer	106	12490.0	1	UniProt (A0AAA9WX15)	Oryctolagus cuniculus (rabbit)
79	AC (Bp)	60S ribosomal protein L37a	polymer	92	10299.4	1	UniProt (G1SY53) Pfam (PF01780)	Oryctolagus cuniculus (rabbit)	eL43
80	BC (Br)	[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B	polymer	137	15697.5	1	UniProt (A0A8C0DF35) Pfam (PF01778)	Oryctolagus cuniculus (rabbit)	[histone H4]-lysine20 N-methyltransferase KMT5B
81	CC (Bs)	Large ribosomal subunit protein uL10	polymer	318	34380.5	1	UniProt (G1SPK4) Pfam (PF00466) Pfam (PF17777) Pfam (PF00428)	Oryctolagus cuniculus (rabbit)	uL10
82	DC (Bt)	60S ribosomal protein L12	polymer	165	17847.6	1	UniProt (G1SMR7) Pfam (PF03946) Pfam (PF00298)	Oryctolagus cuniculus (rabbit)
83	EC (Bv)	Ribosomal protein uL1	polymer	217	24875.4	1	UniProt (G1SKZ8) Pfam (PF00687)	Oryctolagus cuniculus (rabbit)
84	FC (MA)	Glycylpeptide N-tetradecanoyltransferase 1	polymer	496	56791.9	1	UniProt (P30419) Pfam (PF01233) Pfam (PF02799)	Homo sapiens (human)	Myristoyl-CoA:protein N-myristoyltransferase 1,HsNMT1,NMT 1,Type I N-myristoyltransferase,Peptide N-myristoyltransferase 1,Protein-lysine myristoyltransferase NMT1
85	GC (Nt)	Nascent polypeptide-associated complex subunit alpha	polymer	215	23406.8	1	UniProt (Q13765) Pfam (PF01849) Pfam (PF19026)	Homo sapiens (human)	NAC-alpha,Alpha-NAC
86	HC (Nu)	Isoform 2 of Transcription factor BTF3	polymer	162	17724.0	1	UniProt (P20290) Pfam (PF01849)	Homo sapiens (human)	Nascent polypeptide-associated complex subunit beta,NAC-beta,RNA polymerase B transcription factor 3
87	AD, AE, AF, AG, AJ... (A2, B5, B7, BP, BR...)	MAGNESIUM ION	non-polymer		24.3	407	Chemie (MG)
88	AAA, AH, AS, AV, AW... (BN, A2, B5, BQ, Ad...)	UNKNOWN ATOM OR ION	non-polymer		145.2	187	Chemie (UNX)
89	AT, BT, CT, DT, ET... (B5, A2)	SPERMIDINE	non-polymer		145.2	30	Chemie (SPD)
90	MR, NR, VH (B5, A2)	SPERMINE	non-polymer		202.3	3	Chemie (SPM)
91	AI, BI, CI, MAA, NAA... (AC, AE, AG, Bg, Bj...)	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
92	ABA, BBA, CBA, DBA, EBA... (Ap, Ar, As, At, Aw...)	water	water		18.0	2028	Chemie (HOH)

Sequence modifications

AZ: 2 - 295 (UniProt: G1TLT8)

PDB	External Database	Details
Ace 2	-	acetylation

Ab: 1 - 293 (UniProt: O18789)

PDB	External Database	Details
Ile 33	Val 33	conflict
Ala 101	Ser 101	conflict

Ad: 1 - 263 (UniProt: G1TK17)

PDB	External Database	Details
Gly 25	Ser 25	conflict
Arg 51	Lys 51	conflict
Thr 78	Ala 78	conflict
Val 156	Met 156	conflict

Ah: 1 - 208 (UniProt: G1TJW1)

PDB	External Database	Details
Arg 47	Gly 47	conflict

Ar: 2 - 152 (UniProt: G1TPG3)

PDB	External Database	Details
Ace 2	-	acetylation

As: 1 - 145 (UniProt: G1TN62)

PDB	External Database	Details
Gly 119	Trp 119	conflict
Asn 142	Lys 142	conflict

Au: 1 - 83 (UniProt: G1TM82)

PDB	External Database	Details
Ace 0	-	acetylation

B5: 1 - 4808 (GenBank: GBCN01009604.1)

PDB	External Database	Details
Uy1 3550	U 5943	conflict

BC: 2 - 413 (UniProt: G1SVW5)

PDB	External Database	Details
Ace 2	-	acetylation

BF: 1 - 247 (UniProt: G1TUB1)

PDB	External Database	Details
Arg 61	Gly 61	conflict
Arg 93	Gly 93	conflict
Met 131	Val 131	conflict
Ile 153	Val 153	conflict

BG: 1 - 266 (UniProt: P62424)

PDB	External Database	Details
Leu 184	Ile 184	conflict

BL: 1 - 211 (UniProt: G1TKB3)

PDB	External Database	Details
Arg 74	His 74	conflict
Arg 190	His 190	conflict

BQ: 1 - 188 (UniProt: F6QKI9)

PDB	External Database	Details
Arg 134	Cys 134	conflict

BR: 1 - 196 (UniProt: G1TJR3)

PDB	External Database	Details
Arg 38	Cys 38	conflict
Arg 64	Gln 64	conflict
Thr 94	Lys 94	conflict

BU: 1 - 128 (UniProt: G1TSG1)

PDB	External Database	Details
Gly 32	Arg 32	conflict
Ala 36	Glu 36	conflict
Phe 39	Ser 39	conflict
Gly 54	Arg 54	conflict
Arg 97	His 97	conflict

Bk: 1 - 70 (UniProt: G1U001)

PDB	External Database	Details
Lys 24	Asn 24	conflict

Br: 2 - 137 (UniProt: A0A8C0DF35)

PDB	External Database	Details
Ace 2	-	acetylation

MA: 1 - 496 (UniProt: P30419)

PDB	External Database	Details
Ala 180	Tyr 180	engineered mutation

Sequence viewer

Contents of the asymmetric unit

Polymers	Number of chains	86
Polymers	Total formula weight	3911946.3
Non-Polymers*	Number of molecules	635
Non-Polymers*	Total formula weight	42540.8
All*	Total formula weight	3954487.1

*Water molecules are not included.

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)