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9QPC

DNA polymerase with inhibitor

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase III PolC-typepolymer1474166595.81UniProt (A0AAP9BNN1)Enterococcus faeciumPolIII
2B
(E)
DNA (5'-D(P*TP*AP*A)-3')polymer3885.61Escherichia coli
3C
(P)
DNA (5'-D(P*TP*AP*GP*GP*TP*GP*CP*GP*CP*AP*T)-3')polymer3310179.61Escherichia coli
4D
(T)
DNA (5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*AP*CP*CP*TP*A)-3')polymer4212724.11Escherichia coli
5E
(A)
5-[[2,2-bis(fluoranyl)-1,3-benzodioxol-5-yl]methylamino]-3-fluoranyl-1-(2-hydroxyethyl)-6~{H}-pyrazolo[4,3-d]pyrimidin-7-onenon-polymer383.31Chemie (A1I88)
6F, G, H, I
(A)
ZINC IONnon-polymer65.44Chemie (ZN)
7J, K
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
8L
(A)
waterwater18.03Chemie (HOH)
Sequence modifications
A: 1 - 1452 (UniProt: A0AAP9BNN1)
PDBExternal DatabaseDetails
Met -21-initiating methionine
Gly -20-expression tag
Ser -19-expression tag
Ser -18-expression tag
His -17-expression tag
His -16-expression tag
His -15-expression tag
His -14-expression tag
His -13-expression tag
His -12-expression tag
Ser -11-expression tag
Ser -10-expression tag
Gly -9-expression tag
Leu -8-expression tag
Val -7-expression tag
Pro -6-expression tag
Arg -5-expression tag
Gly -4-expression tag
Ser -3-expression tag
His -2-expression tag
Met -1-expression tag
His 0-expression tag
Thr 63Ala 63conflict
Ile 68Val 68conflict
Asp 72Glu 72conflict
His 218-insertion
Ile 219-insertion
Ser 236Asn 234conflict
Val 290Ile 288conflict
Ile 323Val 321conflict
Ser 423Asn 421conflict
Ala 431Asp 429engineered mutation
Ala 433Glu 431engineered mutation
Gly 484Glu 482conflict
Asp 505Gly 503conflict
Asn 595His 593conflict
Glu 801Asp 799conflict
Lys 857Glu 855conflict
Ser 1141Thr 1139conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight190385.1
Non-Polymers*Number of molecules7
Total formula weight693.5
All*Total formula weight191078.6
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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