9QP4
Pre-active dark-state structure of human short-wave-sensitive opsin (OPN1SW)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Short-wave-sensitive opsin 1,Soluble cytochrome b562 | polymer | 488 | 54494.8 | 1 | UniProt (P03999) UniProt (P0ABE7) Pfam (PF00001) | Homo sapiens (human) | Blue cone photoreceptor pigment,Blue-sensitive opsin,BOP,Cytochrome b-562 |
| 2 | B (L) | Light chain BRIL Fab SRP2070 | polymer | 215 | 23812.3 | 1 | synthetic construct | ||
| 3 | C (H) | Heavy chain BRIL Fab SRP2070 | polymer | 222 | 24033.9 | 1 | synthetic construct | ||
| 4 | D (A) | RETINAL | non-polymer | 284.4 | 1 | Chemie (RET) PubChem (638015) PubChem (5381765) |
Sequence modifications
A: 1 - 230 (UniProt: P03999)
A: 892 - 996 (UniProt: P0ABE7)
A: 232 - 345 (UniProt: P03999)
A: 892 - 996 (UniProt: P0ABE7)
| PDB | External Database | Details |
|---|---|---|
| Trp 898 | Met 29 | conflict |
| Ile 993 | His 124 | conflict |
| Leu 997 | - | linker |
| Arg 998 | - | linker |
| Ser 999 | - | linker |
| Thr 1000 | - | linker |
| Leu 1001 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ala 887 | - | linker |
| Arg 888 | - | linker |
| Arg 889 | - | linker |
| Gln 890 | - | linker |
| Leu 891 | - | linker |
| Leu 346 | - | expression tag |
| Glu 347 | - | expression tag |
| Val 348 | - | expression tag |
| Leu 349 | - | expression tag |
| Phe 350 | - | expression tag |
| Gln 351 | - | expression tag |
| Gly 352 | - | expression tag |
| Pro 353 | - | expression tag |
| Asp 354 | - | expression tag |
| Tyr 355 | - | expression tag |
| Lys 356 | - | expression tag |
| Asp 357 | - | expression tag |
| Asp 358 | - | expression tag |
| Asp 359 | - | expression tag |
| Asp 360 | - | expression tag |
| Lys 361 | - | expression tag |
| Gly 362 | - | expression tag |
| Ala 363 | - | expression tag |
| Gly 364 | - | expression tag |
| Ala 365 | - | expression tag |
| Thr 366 | - | expression tag |
| Glu 367 | - | expression tag |
| Thr 368 | - | expression tag |
| Ser 369 | - | expression tag |
| Gln 370 | - | expression tag |
| Val 371 | - | expression tag |
| Ala 372 | - | expression tag |
| Pro 373 | - | expression tag |
| Ala 374 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 102340.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 284.4 | |
| All* | Total formula weight | 102625.4 |
