9QK1

GABA-A receptor a2b3 (1:4) + a2NB06(silent) + b3Mb125 + GABA

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Gamma-aminobutyric acid receptor subunit alpha-2	polymer	365	41495.5	1	UniProt (P47869)	Homo sapiens (human)	GABA(A) receptor subunit alpha-2,GABAAR subunit alpha-2
2	B, C, D, E (B, C, D, E)	Gamma-aminobutyric acid receptor subunit beta-3,Soluble cytochrome b562	polymer	451	51615.1	4	UniProt (P28472) UniProt (P0ABE7)	Homo sapiens (human)	GABA(A) receptor subunit beta-3,GABAAR subunit beta-3,Cytochrome b-562
3	F (F)	a2NB06	polymer	133	14408.7	1		Lama glama
4	G, H, I (G, H, I)	Mb125	polymer	133	14771.2	3		Lama glama
5	J, L, N, P (L, N, P, R)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
6	K, M, O, Q (M, O, Q, S)	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	4	In PDB GlyTouCan (G22573RC)
7	R, S (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG) PubChem (24139)
8	T (B)	GAMMA-AMINO-BUTANOIC ACID	non-polymer		103.1	1	Chemie (ABU) PubChem (119)
9	U, V, W (C, D, E)	HISTAMINE	non-polymer		111.1	3	Chemie (HSM)

Sequence modifications

A: 1 - 311 (UniProt: P47869)

PDB	External Database	Details
Ser 312	-	expression tag
Gln 313	-	expression tag
Pro 314	-	expression tag
Ala 315	-	expression tag
Arg 316	-	expression tag
Ala 317	-	expression tag
Ala 318	-	expression tag
Lys 388	-	expression tag
Ile 389	-	expression tag
Asp 390	-	expression tag
Arg 391	-	expression tag
Met 392	-	expression tag
Ser 393	-	expression tag
Arg 394	-	expression tag
Ile 395	-	expression tag
Val 396	-	expression tag
Phe 397	-	expression tag
Pro 398	-	expression tag
Val 399	-	expression tag
Leu 400	-	expression tag
Phe 401	-	expression tag
Gly 402	-	expression tag
Thr 403	-	expression tag
Phe 404	-	expression tag
Asn 405	-	expression tag
Leu 406	-	expression tag
Val 407	-	expression tag
Tyr 408	-	expression tag
Trp 409	-	expression tag
Ala 410	-	expression tag
Thr 411	-	expression tag
Tyr 412	-	expression tag
Leu 413	-	expression tag
Asn 414	-	expression tag
Arg 415	-	expression tag
Glu 416	-	expression tag
Pro 417	-	expression tag
Val 418	-	expression tag
Leu 419	-	expression tag
Gly 420	-	expression tag
Val 421	-	expression tag
Ser 422	-	expression tag
Pro 423	-	expression tag
Gly 424	-	expression tag
Thr 425	-	expression tag
Thr 426	-	expression tag
Glu 427	-	expression tag
Thr 428	-	expression tag
Ser 429	-	expression tag
Gln 430	-	expression tag
Val 431	-	expression tag
Ala 432	-	expression tag
Pro 433	-	expression tag
Ala 434	-	expression tag

B, C, D, E: 1 - 307 (UniProt: P28472)
B, C, D, E: 308 - 415 (UniProt: P0ABE7)

PDB	External Database	Details
Trp 308	Met 29	conflict
Ile 312	His 124	conflict
Leu 416	-	linker
Thr 417	-	linker
Gly 418	-	linker
Arg 419	-	linker
Ala 420	-	linker
Ala 421	-	linker

B, C, D, E: 422 - 448 (UniProt: P28472)

PDB	External Database	Details
Ser 308	-	linker
Gln 308	-	linker
Pro 308	-	linker
Ala 308	-	linker
Gly 308	-	linker
Thr 308	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	306678.3
Branched	Number of molecules	8
	Total formula weight	4692.3
Non-Polymers*	Number of molecules	6
	Total formula weight	879.0
All*	Total formula weight	312249.6

*Water molecules are not included.